Makiko Mochizuki-Kashio
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Explore the profile of Makiko Mochizuki-Kashio including associated specialties, affiliations and a list of published articles.
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26
Citations
767
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Recent Articles
1.
Dorrell C, Peters A, Zhang Q, Balaji N, Baradar K, Mochizuki-Kashio M, et al.
Pediatr Blood Cancer
. 2024 May;
71(8):e31030.
PMID: 38733122
Fanconi anemia (FA) is a disease caused by defective deoxyribonucleic acid (DNA) repair that manifests as bone marrow failure, cancer predisposition, and developmental defects. We previously reported that monotherapy with...
2.
Yahagi A, Mochizuki-Kashio M, Sorimachi Y, Takubo K, Nakamura-Ishizu A
Exp Hematol
. 2024 Mar;
135:104191.
PMID: 38493949
Erythropoiesis in the adult bone marrow relies on mitochondrial membrane transporters to facilitate heme and hemoglobin production. Erythrocytes in the bone marrow are produced although the differentiation of erythroid progenitor...
3.
Sahoo S, Abdelhamed S, Mochizuki-Kashio M, Wahlster L
Front Oncol
. 2024 Mar;
14:1377974.
PMID: 38434687
No abstract available.
4.
Kovuru N, Mochizuki-Kashio M, Menna T, Jeffrey G, Hong Y, Yoon Y, et al.
Nat Commun
. 2024 Feb;
15(1):1852.
PMID: 38424108
Demand-adjusted and cell type specific rates of protein synthesis represent an important safeguard for fate and function of long-term hematopoietic stem cells. Here, we identify increased protein synthesis rates in...
5.
Dorrell C, Peters A, Zhang Q, Balaji N, Baradar K, Mochizuki-Kashio M, et al.
bioRxiv
. 2023 Aug;
PMID: 37649908
Fanconi Anemia (FA) is a disease caused by defective DNA repair which manifests as bone marrow failure, cancer predisposition, and developmental defects. Mice containing inactivating mutations in one or more...
6.
Mochizuki-Kashio M, Otsuki N, Fujiki K, Abdelhamd S, Kurre P, Grompe M, et al.
Front Oncol
. 2023 Apr;
13:1108430.
PMID: 37007148
Fanconi Anemia (FA) is an inherited bone marrow (BM) failure disorder commonly diagnosed during school age. However, in murine models, disrupted function of FA genes leads to a much earlier...
7.
Mochizuki-Kashio M, Shiozaki H, Suda T, Nakamura-Ishizu A
Int J Mol Sci
. 2021 Apr;
22(9).
PMID: 33924874
Hematopoietic stem cells (HSCs) reside in a hypoxic microenvironment that enables glycolysis-fueled metabolism and reduces oxidative stress. Nonetheless, metabolic regulation in organelles such as the mitochondria and lysosomes as well...
8.
Nakamura-Ishizu A, Chin D, Matsumura T, Tan D, Mochizuki-Kashio M, Jianwen D, et al.
Blood
. 2021 Mar;
137(19):2609-2620.
PMID: 33657206
Hematopoietic stem cells (HSC) rarely divide, rest in quiescence, and proliferate only upon stress hematopoiesis. The cytokine thrombopoietin (Thpo) has been perplexingly described to induce quiescence and promote self-renewal divisions...
9.
Aoyama K, Oshima M, Koide S, Suzuki E, Mochizuki-Kashio M, Kato Y, et al.
iScience
. 2018 Nov;
9:161-174.
PMID: 30396150
Polycomb repressive complex (PRC) 2 represses transcription through histone H3K27 trimethylation (H3K27me3). We previously reported that the hematopoietic-cell-specific deletion of Ezh2, encoding a PRC2 enzyme, induced myelodysplastic syndrome (MDS) in...
10.
Wang C, Oshima M, Sato D, Matsui H, Kubota S, Aoyama K, et al.
J Clin Invest
. 2018 Aug;
128(9):3872-3886.
PMID: 30080177
Early T cell precursor acute lymphoblastic leukemia (ETP-ALL) is a new pathological entity with poor outcomes in T cell ALL (T-ALL) that is characterized by a high incidence of loss-of-function...