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Goro Sashida

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Articles 94
Citations 1711
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Recent Articles
1.
Sashida G
Rinsho Ketsueki . 2024 Aug; 65(7):702-708. PMID: 39098022
Myelodysplastic syndrome (MDS) is a refractory cancer that arises from hematopoietic stem cells and predominantly affects elderly adults. In addition to driver gene mutations, which are also found in clonal...
2.
Niibori-Nambu A, Wang C, Chin D, Chooi J, Hosoi H, Sonoki T, et al.
Gene . 2024 Jul; 928:148761. PMID: 39002785
Leukemia stem cells (LSCs) are widely believed to reside in well-characterized bone marrow (BM) niches; however, the capacity of the BM niches to accommodate LSCs is insufficient, and a significant...
3.
Sashida G
Exp Hematol . 2024 Jun; 135:104251. PMID: 38851479
No abstract available.
4.
Kubota S, Sun Y, Morii M, Bai J, Ideue T, Hirayama M, et al.
EMBO J . 2024 May; 43(13):2661-2684. PMID: 38811851
The molecular mechanisms governing the response of hematopoietic stem cells (HSCs) to stress insults remain poorly defined. Here, we investigated effects of conditional knock-out or overexpression of Hmga2 (High mobility...
5.
Morii M, Kubota S, Iimori M, Yokomizo-Nakano T, Hamashima A, Bai J, et al.
Leukemia . 2024 May; 38(6):1275-1286. PMID: 38734786
TIF1β/KAP1/TRIM28, a chromatin modulator, both represses and activates the transcription of genes in normal and malignant cells. Analyses of datasets on leukemia patients revealed that the expression level of TIF1β...
6.
Sashida G
Int J Hematol . 2023 May; 117(6):789-790. PMID: 37191835
In this issue of PIH, we asked four researchers to write about basic research on the molecular mechanisms of the development of myeloid malignancies, in particular two epigenetic regulation and...
7.
Yokomizo-Nakano T, Hamashima A, Kubota S, Bai J, Sorin S, Sun Y, et al.
J Exp Med . 2023 Apr; 220(7). PMID: 37071125
Aberrant innate immune signaling in myelodysplastic syndrome (MDS) hematopoietic stem/progenitor cells (HSPCs) has been implicated as a driver of the development of MDS. We herein demonstrated that a prior stimulation...
8.
Kawano S, Araki K, Bai J, Furukawa I, Tateishi K, Yoshinobu K, et al.
Cancer Sci . 2023 Mar; 114(7):2821-2834. PMID: 36945113
MicroRNAs (miRNAs) play a crucial role in regulating gene expression. MicroRNA expression levels fluctuate, and point mutations and methylation occur in cancer cells; however, to date, there have been no...
9.
Kameda T, Shide K, Kamiunten A, Kogure Y, Morishita D, Koya J, et al.
Commun Biol . 2022 Nov; 5(1):1309. PMID: 36446869
Adult T-cell leukemia/lymphoma (ATL) is caused by human T-cell leukemia virus type 1 (HTLV-1). In addition to HTLV-1 bZIP factor (HBZ), a leukemogenic antisense transcript of HTLV-1, abnormalities of genes...
10.
Sorin S, Kubota S, Hamidi S, Yokomizo-Nakano T, Vaeteewoottacharn K, Wongkham S, et al.
FASEB J . 2022 May; 36(7):e22345. PMID: 35635715
High mobility group nucleosome-binding protein 3 (HMGN3), a member of the HMGN family, modulates the structure of chromatin and regulates transcription through transcription factors. HMGN3 has been implicated in the...