Maja S Engelstoft
Overview
Explore the profile of Maja S Engelstoft including associated specialties, affiliations and a list of published articles.
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22
Citations
1239
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Recent Articles
11.
Grunddal K, Ratner C, Svendsen B, Sommer F, Engelstoft M, Madsen A, et al.
Endocrinology
. 2015 Oct;
157(1):176-94.
PMID: 26469136
The 2 gut hormones glucagon-like peptide-1 (GLP-1) and peptide YY (PYY) are well known to be coexpressed, costored, and released together to coact in the control of key metabolic target...
12.
Engelstoft M, Lund M, Grunddal K, Egerod K, Osborne-Lawrence S, Poulsen S, et al.
Mol Endocrinol
. 2015 Sep;
29(11):1658-71.
PMID: 26352512
Chromogranin A (ChgA) is an acidic protein found in large dense-core secretory vesicles and generally considered to be expressed in all enteroendocrine cells of the gastrointestinal (GI) tract. Here, we...
13.
Egerod K, Engelstoft M, Lund M, Grunddal K, Zhao M, Barir-Jensen D, et al.
Endocrinology
. 2015 Jul;
156(11):3909-23.
PMID: 26181106
In the stomach, somatostatin (SST) acts as a general paracrine negative regulator of exocrine secretion of gastric acid and pepsinogen and endocrine secretion of gastrin, ghrelin, and histamine. Using reporter...
14.
Hauge M, Vestmar M, Husted A, Ekberg J, Wright M, Di Salvo J, et al.
Mol Metab
. 2015 Feb;
4(1):3-14.
PMID: 25685685
Objectives: GPR40 (FFAR1), a clinically proven anti-diabetes target, is a Gq-coupled receptor for long chain fatty acids (LCFA) stimulating insulin secretion directly and mediating a major part of the dietary...
15.
Panaro B, Tough I, Engelstoft M, Matthews R, Digby G, Moller C, et al.
Cell Metab
. 2014 Dec;
20(6):1018-29.
PMID: 25453189
The melanocortin-4 receptor (MC4R) is expressed in the brainstem and vagal afferent nerves and regulates a number of aspects of gastrointestinal function. Here we show that the receptor is also...
16.
Engelstoft M, Park W, Sakata I, Kristensen L, Husted A, Osborne-Lawrence S, et al.
Mol Metab
. 2013 Dec;
2(4):376-92.
PMID: 24327954
The molecular mechanisms regulating secretion of the orexigenic-glucoregulatory hormone ghrelin remain unclear. Based on qPCR analysis of FACS-purified gastric ghrelin cells, highly expressed and enriched 7TM receptors were comprehensively identified...
17.
Engelstoft M, Egerod K, Lund M, Schwartz T
Curr Opin Pharmacol
. 2013 Oct;
13(6):912-21.
PMID: 24140256
The GI-tract is profoundly involved in the control of metabolism through peptide hormones secreted from enteroendocrine cells scattered throughout the gut mucosa. A large number of recently generated transgenic reporter...
18.
Nohr M, Pedersen M, Gille A, Egerod K, Engelstoft M, Husted A, et al.
Endocrinology
. 2013 Jul;
154(10):3552-64.
PMID: 23885020
The expression of short-chain fatty acid receptors GPR41/FFAR3 and GPR43/ free fatty acid receptor 2 (FFAR2) was studied in the gastrointestinal tract of transgenic monomeric red fluorescent protein (mRFP) reporter...
19.
Egerod K, Engelstoft M, Grunddal K, Nohr M, Secher A, Sakata I, et al.
Endocrinology
. 2012 Oct;
153(12):5782-95.
PMID: 23064014
Enteroendocrine cells such as duodenal cholecystokinin (CCK cells) are generally thought to be confined to certain segments of the gastrointestinal (GI) tract and to store and release peptides derived from...
20.
Sivertsen B, Lang M, Frimurer T, Holliday N, Bach A, Els S, et al.
J Biol Chem
. 2011 Mar;
286(23):20845-60.
PMID: 21402696
Based on the conformationally constrained D-Trp-Phe-D-Trp (wFw) core of the prototype inverse agonist [D-Arg(1),D-Phe(5),D-Trp(7,9),Leu(11)]substance P, a series of novel, small, peptide-mimetic agonists for the ghrelin receptor were generated. By using...