Mahesh S Desai
Overview
Explore the profile of Mahesh S Desai including associated specialties, affiliations and a list of published articles.
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36
Citations
2294
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Recent Articles
1.
Metwaly A, Kriaa A, Hassani Z, Carraturo F, Druart C, Arnauts K, et al.
Nat Rev Gastroenterol Hepatol
. 2025 Mar;
PMID: 40033063
The gut microbiome comprises trillions of microorganisms and profoundly influences human health by modulating metabolism, immune responses and neuronal functions. Disruption in gut microbiome composition is implicated in various inflammatory...
2.
Rous C, Cadiou J, Yazbek H, Monzel E, Desai M, Dore J, et al.
Microbiol Spectr
. 2025 Feb;
13(3):e0151724.
PMID: 39907460
Importance: In this article, the authors explore the impact of a diet with reduced fiber content on the gut microbiota-host symbiosis in a mouse model. More importantly, they examine the...
3.
Monzel E, Desai M
Cell Host Microbe
. 2024 Nov;
32(11):1875-1877.
PMID: 39541940
The functions of non-coding small RNAs (sRNAs) within the human microbiome remain largely unexplored. In this Cell Host & Microbe issue, El Mouali et al. identify Segatella RNA colonization factor...
4.
Grant E, Parrish A, Boudaud M, Hunewald O, Hirayama A, Ollert M, et al.
Microbiome
. 2024 Sep;
12(1):179.
PMID: 39307855
Background: Dietary fibers can alter microbial metabolic output in support of healthy immune function; however, the impact of distinct fiber sources and immunomodulatory effects beyond short-chain fatty acid production are...
5.
Anderson C, Boeckaerts L, Chin P, Cardas J, Xie W, Goncalves A, et al.
Cell Host Microbe
. 2024 Aug;
32(9):1469-1487.e9.
PMID: 39197455
Cytotoxic chemotherapies have devastating side effects, particularly within the gastrointestinal tract. Gastrointestinal toxicity includes the death and damage of the epithelium and an imbalance in the intestinal microbiota, otherwise known...
6.
Steimle A, Neumann M, Grant E, Willieme S, De Sciscio A, Parrish A, et al.
Nat Microbiol
. 2024 Jul;
9(9):2244-2261.
PMID: 39009690
Gut bacteria are linked to neurodegenerative diseases but the risk factors beyond microbiota composition are limited. Here we used a pre-clinical model of multiple sclerosis (MS), experimental autoimmune encephalomyelitis (EAE),...
7.
Grant E, De Franco H, Desai M
Trends Endocrinol Metab
. 2024 Jul;
36(1):70-82.
PMID: 38991905
Dietary fiber is degraded by commensal gut microbes to yield host-beneficial short-chain fatty acids (SCFAs), but personalized responses to fiber supplementation highlight a role for other microbial metabolites in shaping...
8.
Wolter M, Grant E, Boudaud M, Pudlo N, Pereira G, Eaton K, et al.
Mol Syst Biol
. 2024 May;
20(6):596-625.
PMID: 38745106
The erosion of the colonic mucus layer by a dietary fiber-deprived gut microbiota results in heightened susceptibility to an attaching and effacing pathogen, Citrobacter rodentium. Nevertheless, the questions of whether...
9.
Vasconcelos Pereira G, Boudaud M, Wolter M, Alexander C, De Sciscio A, Grant E, et al.
Cell Host Microbe
. 2024 Mar;
32(4):527-542.e9.
PMID: 38513656
Inflammatory bowel diseases (IBDs) are chronic conditions characterized by periods of spontaneous intestinal inflammation and are increasing in industrialized populations. Combined with host genetics, diet and gut bacteria are thought...
10.
Gaifem J, Mendes-Frias A, Wolter M, Steimle A, Garzon M, Ubeda C, et al.
mBio
. 2024 Mar;
15(4):e0007824.
PMID: 38470269
Importance: The contribution of the gut microbiome to the balance between homeostasis and inflammation is widely known. Nevertheless, the etiology of inflammatory bowel disease, which is known to be influenced...