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Eric C Martens

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Articles 119
Citations 9470
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Recent Articles
1.
Sharma M, Pudlo N, Jarva M, Kaur A, John A, Burchill L, et al.
J Biol Chem . 2025 Feb; :108320. PMID: 39956340
The production of short-chain fatty acids (SCFAs) by Firmicutes (Bacillota) within the human gastrointestinal tract is recognized as critical for gut health and the progression of a range of disease...
2.
Brown H, Morris A, Pudlo N, Hopkins A, Martens E, Golob J, et al.
mBio . 2024 Nov; 15(12):e0150624. PMID: 39565129
Importance: Acarbose is a type 2 diabetes medication that works primarily by stopping starch breakdown into glucose in the small intestine. This is accomplished by the inhibition of host enzymes,...
3.
Hayase E, Hayase T, Mukherjee A, Stinson S, Jamal M, Ortega M, et al.
Cell Host Microbe . 2024 Aug; 32(9):1621-1636.e6. PMID: 39214085
Acute lower gastrointestinal GVHD (aLGI-GVHD) is a serious complication of allogeneic hematopoietic stem cell transplantation. Although the intestinal microbiota is associated with the incidence of aLGI-GVHD, how the intestinal microbiota...
4.
Schaus S, Vasconcelos Pereira G, Luis A, Madlambayan E, Terrapon N, Ostrowski M, et al.
mBio . 2024 Jul; 15(8):e0003924. PMID: 38975756
Symbiotic interactions between humans and our communities of resident gut microbes (microbiota) play many roles in health and disease. Some gut bacteria utilize mucus as a nutrient source and can...
5.
Brown H, Morris A, Pudlo N, Hopkins A, Martens E, Golob J, et al.
bioRxiv . 2024 Jun; PMID: 38826241
Acarbose is a type-2 diabetes medicine that inhibits dietary starch breakdown into glucose by inhibiting host amylase and glucosidase enzymes. Numerous gut species in the genus enzymatically break down starch...
6.
Wolter M, Grant E, Boudaud M, Pudlo N, Pereira G, Eaton K, et al.
Mol Syst Biol . 2024 May; 20(6):596-625. PMID: 38745106
The erosion of the colonic mucus layer by a dietary fiber-deprived gut microbiota results in heightened susceptibility to an attaching and effacing pathogen, Citrobacter rodentium. Nevertheless, the questions of whether...
7.
Xu H, Pudlo N, Cantu-Jungles T, Tuncil Y, Nie X, Kaur A, et al.
ISME Commun . 2024 Apr; 4(1):ycae037. PMID: 38645272
Structurally complex corn bran arabinoxylan (CAX) was used as a model glycan to investigate gut bacteria growth and competition on different AX-based fine structures. Nine hydrolyzate segments of the CAX...
8.
Vasconcelos Pereira G, Boudaud M, Wolter M, Alexander C, De Sciscio A, Grant E, et al.
Cell Host Microbe . 2024 Mar; 32(4):527-542.e9. PMID: 38513656
Inflammatory bowel diseases (IBDs) are chronic conditions characterized by periods of spontaneous intestinal inflammation and are increasing in industrialized populations. Combined with host genetics, diet and gut bacteria are thought...
9.
Schaus S, Vasconcelos Periera G, Luis A, Madlambayan E, Terrapon N, Ostrowski M, et al.
bioRxiv . 2024 Jan; PMID: 38293123
Importance: An important facet of maintaining healthy symbiosis between host and intestinal microbes is the mucus layer, the first defense protecting the epithelium from lumenal bacteria. Some gut bacteria degrade...
10.
Wolter M, Grant E, Boudaud M, Pudlo N, Pereira G, Eaton K, et al.
bioRxiv . 2024 Jan; PMID: 38168188
The erosion of the colonic mucus layer by a dietary fiber-deprived gut microbiota results in heightened susceptibility to an attaching and effacing pathogen, . Nevertheless, the questions of whether and...