Mahaboobkhan Rasool
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Explore the profile of Mahaboobkhan Rasool including associated specialties, affiliations and a list of published articles.
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74
Citations
853
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Recent Articles
21.
Thirupataiah B, Mounika G, Reddy G, Sandeep Kumar J, Hossain K, Medishetti R, et al.
Eur J Med Chem
. 2021 May;
221:113514.
PMID: 33992926
While anti-inflammatory properties of isocoumarins are known their PDE4 inhibitory potential was not explored previously. In our effort the non-PDE4 inhibitor isocoumarins were transformed into the promising inhibitors via introducing...
22.
Samarpita S, Rasool M
Cytokine
. 2021 Apr;
142:155502.
PMID: 33810944
Interleukin (IL)-17A signaling pathway plays a critical role in the initiation and progression of rheumatoid arthritis (RA) and represents a viable target for RA therapy. Cyanidin, a flavonoid compound, is...
23.
Dinesh P, Kalaiselvan S, Sujitha S, Rasool M
Inflammation
. 2020 Sep;
44(1):229-242.
PMID: 32876895
Inflammation is a complex biological process which alters the normal physiological function of the immune system resulting in an abnormal microenvironment that leads to several clinical complications. The process of...
24.
Dinesh P, Kalaiselvan S, Sujitha S, Rasool M
J Cell Physiol
. 2020 May;
235(12):9497-9509.
PMID: 32372426
Bone erosion is the major cause of deformities in autoimmune disease conditions such as osteoporosis and rheumatoid arthritis. Aberrant receptor activator of nuclear factor kappa B ligand (RANKL) secretion in...
25.
Dinesh P, Kalaiselvan S, Sujitha S, Rasool M
Int Immunopharmacol
. 2020 Feb;
82:106328.
PMID: 32088641
Fibroblast-like synoviocytes (FLS) lining the arthritic synovial joint region have been implicated to be a key player in bone remodeling. The uncontrolled proliferation of this cell subtype is strictly regulated...
26.
Sujitha S, Dinesh P, Rasool M
Eur J Pharm Biopharm
. 2020 Feb;
149:170-191.
PMID: 32068029
Bone erosion is a debilitating pathological process of osteopathic disorder like rheumatoid arthritis (RA). Current treatment strategies render low disease activity but with disease recurrence. To find an alternative, we...
27.
Samarpita S, Ganesan R, Rasool M
Toxicol Appl Pharmacol
. 2020 Feb;
391:114917.
PMID: 32044269
The hyperplastic phenotype of fibroblast-like synoviocytes (FLSs) plays an important role for synovitis, chronic inflammation and joint destruction in rheumatoid arthritis (RA). Interleukin 17A (IL-17A), a signature pro-inflammatory cytokine effectively...
28.
Sundaram M, Neog M, Rasool M, Kumar G, Hemshekhar M, Kemparaju K, et al.
Phytomedicine
. 2019 Aug;
64:152924.
PMID: 31465983
Background: Arthritis is a common degenerative joint disease characterized by deterioration of articular cartilage, subchondral bone, and associated with immobility, pain and inflammation. The incessant action of reactive oxygen species...
29.
Sujitha S, Rasool M
Int Immunopharmacol
. 2019 Jul;
74:105703.
PMID: 31261037
Drug-induced microRNAs manifest significant therapeutic approaches; however, such progress in the treatment of osteopathic disorders including osteoporosis and rheumatoid arthritis still remains obscure. Contrarily, non-specific drug delivery, at high doses,...
30.
Dinesh P, Rasool M
Apoptosis
. 2019 May;
24(7-8):644-661.
PMID: 31111379
In our previous study, we explored the therapeutic effect of berberine (BBR) against IL-21/IL-21R mediated inflammatory proliferation of adjuvant-induced arthritic fibroblast-like synoviocytes (AA-FLS) through the PI3K/Akt pathway. The current study...