Mahaboobkhan Rasool
Overview
Explore the profile of Mahaboobkhan Rasool including associated specialties, affiliations and a list of published articles.
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74
Citations
853
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Recent Articles
11.
Bhuktar H, Shukla S, Kakularam K, Battu S, Srikanth M, Srivastava S, et al.
Bioorg Chem
. 2023 May;
138:106606.
PMID: 37210826
The 12R-lipoxygenase (12R-LOX), a (non-heme) iron-containing metalloenzyme belonging to the lipoxygenase (LOX) family catalyzes the conversion of arachidonic acid (AA) to its key metabolites. Studies suggested that 12R-LOX plays a...
12.
Samarpita S, Rasool M
Cytokine
. 2023 Jan;
163:156136.
PMID: 36716676
Dendritic cells (DCs) are the critical players in the puzzle of rheumatoid arthritis (RA) disease pathogenesis. Blockade of DC activation has been shown to curtail Th17 cell differentiation and its...
13.
Jose A, Rasool M
Life Sci
. 2022 Oct;
309:121031.
PMID: 36206833
Choline kinase (ChoK) has been well documented as a major enzyme involved in the anomalous cellular lipid metabolic profile of chronic inflammatory disorders. However, new research has now been unveiled...
14.
Srikanth M, Rasool M
Int Immunopharmacol
. 2022 Apr;
109:108795.
PMID: 35487087
Psoriasis is a highly inflammatory autoimmune-mediated skin disease. The strongest evidence has pointed to the influential role of interleukin (IL) -17A in the aberrant pathology of psoriasis. Henceforth, targeting the...
15.
Srivastava S, Rasool M
Life Sci
. 2022 Apr;
298:120516.
PMID: 35367240
Interleukin 6 (IL-6), a pleiotropic inflammatory cytokine, is produced transiently due to tissue damage and infections. Nonetheless, IL-6 contributes to the host regenerative defense mechanism via classical signaling at the...
16.
Jo S, Samarpita S, Lee J, Lee Y, Son J, Jeong M, et al.
Pharmacol Res
. 2022 Mar;
178:106176.
PMID: 35283302
Rheumatoid arthritis (RA) is a chronic immune-mediated disorder, mainly characterized by synovial inflammation and joint damage. If insufficiently treated, RA can lead to irreversible joint destruction and decreased life expectancy....
17.
Thirupataiah B, Bhuktar H, Mounika G, Reddy G, Sandeep Kumar J, Shukla S, et al.
Bioorg Chem
. 2022 Feb;
121:105667.
PMID: 35182886
In search of potent and new anti-inflammatory agents, we explored a new class of isocoumarin derivatives possessing the 3-oxoalkyl moiety at C-4 position. These compounds were synthesized via the FeCl...
18.
Samarpita S, Rasool M
Int Immunopharmacol
. 2021 Dec;
101(Pt B):108359.
PMID: 34863656
Disturbed Th17/Treg balance is a critical pathological event in the disease progression of rheumatoid arthritis (RA). Recently, emerging studies have demonstrated that CD4 + T helper follicular (Tfh) cells exacerbates...
19.
Srivastava S, Samarpita S, Ganesan R, Rasool M
Immunol Invest
. 2021 Oct;
51(6):1582-1597.
PMID: 34704880
Fibroblast-like synoviocytes (FLS) are the critical effector cells primarily involved in rheumatoid arthritis (RA) disease pathogenesis. Interleukin (IL)-6, a proinflammatory cytokine most abundantly expressed in the rheumatoid synovium, promotes Janus...
20.
Samarpita S, Doss H, Ganesan R, Rasool M
3 Biotech
. 2021 Sep;
11(10):436.
PMID: 34549015
Supplementary Information: The online version contains supplementary material available at 10.1007/s13205-021-02985-4.