Madhulika Dixit
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Explore the profile of Madhulika Dixit including associated specialties, affiliations and a list of published articles.
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44
Citations
783
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Recent Articles
1.
Johnson D, Dixit M, Kirubakaran S
Chem Biol Drug Des
. 2025 Feb;
105(2):e70058.
PMID: 39895370
PTP-PEST (also known as PTPN12) regulates cellular signaling and transduction pathways by dephosphorylating its substrate. PTP-PEST is considered an important drug target owing to its involvement in cancer progression and...
2.
Thirumalai Srinivasan S, Manikandan A, Manoj N, Dixit M, Vemparala S
J Phys Chem B
. 2024 Oct;
128(43):10581-10592.
PMID: 39423851
We study the influence of tyrosine phosphorylation on PTP-PEST, a cytosolic protein tyrosine phosphatase. Utilizing a combination of experimental data and computational modeling, specific tyrosine sites, notably, Y64 and Y88,...
3.
Chandel S, Kumaragurubaran R, Giri H, Dixit M
Methods Mol Biol
. 2023 Sep;
2711:147-162.
PMID: 37776455
This protocol describes a simple and an economical method for isolation of endothelial cells from human umbilical vein. Umbilical cord is easily available postpartum following informed consent, and the method...
4.
Giri H, Dixit M
Methods Mol Biol
. 2023 Sep;
2711:47-62.
PMID: 37776448
Endothelial cells lining the inner surface of blood vessels and lymphatic vessels play an indispensable role in vascular homeostasis. Apart from regulating vessel tone and forming an anti-thrombotic and anti-atherosclerotic...
5.
Mallu A, Sivagurunathan S, Paul D, Aggarwal H, Nathan A, Manikandan A, et al.
Immunology
. 2023 May;
170(1):60-82.
PMID: 37185810
Nutritional availability during fasting and refeeding affects the temporal redistribution of lymphoid and myeloid immune cells among the circulating and tissue-resident pools. Conversely, nutritional imbalance and impaired glucose metabolism are...
6.
Manikandan A, T S S, Manoj N, Vemparala S, Dixit M
Proteins
. 2023 Jan;
91(6):831-846.
PMID: 36645312
The AMP-activated protein kinase (AMPK) is known to be activated by the protein tyrosine phosphatase non-receptor type 12 (PTP-PEST) under hypoxic conditions. This activation is mediated by tyrosine dephosphorylation of...
7.
Chandel S, Manikandan A, Mehta N, Nathan A, Tiwari R, Mohapatra S, et al.
J Cell Sci
. 2020 Dec;
134(1).
PMID: 33323505
Global and endothelial loss of PTP-PEST (also known as PTPN12) is associated with impaired cardiovascular development and embryonic lethality. Although hypoxia is implicated in vascular remodelling and angiogenesis, its effect...
8.
Nandi S, Potunuru U, Kumari C, Nathan A, Gopal J, Menon G, et al.
PLoS One
. 2020 Nov;
15(11):e0242375.
PMID: 33211740
Vasoplegia observed post cardiopulmonary bypass (CPB) is associated with substantial morbidity, multiple organ failure and mortality. Circulating counts of hematopoietic stem cells (HSCs) and endothelial progenitor cells (EPC) are potential...
9.
Mallu A, Vasudevan M, Allanki S, Nathan A, Ravi M, Ramanathan G, et al.
Clin Nutr
. 2020 Sep;
40(3):1247-1259.
PMID: 32863060
Background And Objective: Metabolic disorders including diabetes are associated with immune cell dysfunction. However, the effect of normal glucose metabolism or impairment thereof on immune cell gene expression is not...
10.
Chandel S, Sathis A, Dhar M, Giri H, Nathan A, Samawar S, et al.
Atherosclerosis
. 2020 Jul;
307:1-10.
PMID: 32679352
Background And Aims: Angiopoietin-2 (ANG-2) mediates endothelial inflammation to initiate atherosclerosis and angiogenesis. Here we determined the serum levels of ANG-2 in hyperinsulinemic subjects and whether insulin increases its expression...