M M Rosenkilde
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Explore the profile of M M Rosenkilde including associated specialties, affiliations and a list of published articles.
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33
Citations
1114
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Recent Articles
1.
Barington L, Wanke F, Niss Arfelt K, Holst P, Kurschus F, Rosenkilde M
J Leukoc Biol
. 2018 May;
104(2):313-322.
PMID: 29741800
The seven transmembrane G protein-coupled receptor EBV-induced gene 2 (EBI2), also known as GPR183, is expressed in particular in immune cells. Activated by its endogenous ligands, which are a group...
2.
Getschman A, Imai Y, Larsen O, Peterson F, Wu X, Rosenkilde M, et al.
Proc Natl Acad Sci U S A
. 2017 Nov;
114(47):12460-12465.
PMID: 29109267
Psoriasis is a chronic inflammatory skin disease characterized by the infiltration of T cell and other immune cells to the skin in response to injury or autoantigens. Conventional, as well...
3.
Sparre-Ulrich A, Gabe M, Gasbjerg L, Christiansen C, Svendsen B, Hartmann B, et al.
Biochem Pharmacol
. 2017 Feb;
131:78-88.
PMID: 28237651
Alternative processing of the precursor protein pro-GIP results in endogenously produced GIP(1-30)NH, that by DPP-4 cleavage in vivo results in the metabolite GIP(3-30)NH. We showed previously that GIP(3-30)NH is a...
4.
Krishna B, Spiess K, Poole E, Lau B, Voigt S, Kledal T, et al.
Nat Commun
. 2017 Feb;
8:14321.
PMID: 28148951
Reactivation of human cytomegalovirus (HCMV) in transplant recipients can cause life-threatening disease. Consequently, for transplant recipients, killing latently infected cells could have far-reaching clinical benefits. In vivo, myeloid cells and...
5.
Hassing H, Engelstoft M, Sichlau R, Madsen A, Rehfeld J, Pedersen J, et al.
Biofactors
. 2016 Jun;
42(6):665-673.
PMID: 27297962
The intestinal G protein-coupled receptor GPR119 is a novel metabolic target involving glucagon-like peptide-1 (GLP-1)-derived insulin-regulated glucose homeostasis. Endogenous and diet-derived lipids, including N-acylethanolamines and 2-monoacylglycerols (2-MAG) activate GPR119. The...
6.
Hansen L, Sparre-Ulrich A, Christensen M, Knop F, Hartmann B, Holst J, et al.
Br J Pharmacol
. 2015 Nov;
173(5):826-38.
PMID: 26572091
Background And Purpose: Glucose-dependent insulinotropic polypeptide (GIP) affects lipid, bone and glucose homeostasis. High-affinity ligands for the GIP receptor are needed to elucidate the physiological functions and pharmacological potential of...
7.
Sparre-Ulrich A, Hansen L, Svendsen B, Christensen M, Knop F, Hartmann B, et al.
Br J Pharmacol
. 2015 Sep;
173(1):27-38.
PMID: 26359804
Background And Purpose: Specific, high potency receptor antagonists are valuable tools when evaluating animal and human physiology. Within the glucose-dependent, insulinotropic polypeptide (GIP) system, considerable attention has been given to...
8.
Christensen M, Sparre-Ulrich A, Hartmann B, Grevstad U, Rosenkilde M, Holst J, et al.
Int J Obes (Lond)
. 2015 Aug;
39(11):1651-4.
PMID: 26228460
Treatment with liraglutide leads to weight loss. We investigated whether blood-to-cerebrospinal fluid (CSF) transfer of liraglutide occurs, and if so, whether it associates with clinical weight loss following liraglutide treatment...
9.
Thiele S, Mungalpara J, Steen A, Rosenkilde M, Vabeno J
Br J Pharmacol
. 2014 Jul;
171(23):5313-29.
PMID: 25039237
Background And Purpose: The cyclopentapeptide FC131 (cyclo(-L-Arg(1) -L-Arg(2) -L-2-Nal(3) -Gly(4) -D-Tyr(5) -)) is an antagonist at the CXC chemokine receptor CXCR4, which plays a role in human immunodeficiency virus infection,...
10.
Steen A, Sparre-Ulrich A, Thiele S, Guo D, Frimurer T, Rosenkilde M
Br J Pharmacol
. 2013 Dec;
171(6):1566-79.
PMID: 24328926
Background And Purpose: A conserved amino acid within a protein family indicates a significance of the residue. In the centre of transmembrane helix (TM)-5, position V:13/5.47, an aromatic amino acid...