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M L Tsang

Explore the profile of M L Tsang including associated specialties, affiliations and a list of published articles. Areas
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Articles 40
Citations 1219
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Recent Articles
1.
Tsang M, Wong W, Kun K, Tai C, Ng T, Lau K, et al.
Hong Kong Med J . 2004 Oct; 10(5):301-6. PMID: 15479957
Objective: To evaluate the efficacy and safety of arterial embolisation in the management of intractable primary post-partum haemorrhage. DESIGN. Retrospective case series. Setting: Regional hospital, Hong Kong. Patients: Nine patients...
2.
Subklewe M, Paludan C, Tsang M, Mahnke K, Steinman R, Munz C
J Exp Med . 2001 Feb; 193(3):405-11. PMID: 11157061
Dendritic cells (DCs) are not targets for infection by the transforming Epstein-Barr virus (EBV). To test if the adjuvant role of DCs could be harnessed against EBV latency genes by...
3.
Bickham K, Munz C, Tsang M, Larsson M, Fonteneau J, Bhardwaj N, et al.
J Clin Invest . 2001 Jan; 107(1):121-30. PMID: 11134187
The Epstein-Barr virus (EBV) nuclear antigen-1 (EBNA1) maintains the viral episome in all host cells infected with EBV. Recently, EBNA1 was found to be the main EBV latency antigen for...
4.
Munz C, Bickham K, Subklewe M, Tsang M, Chahroudi A, Kurilla M, et al.
J Exp Med . 2000 May; 191(10):1649-60. PMID: 10811859
The Epstein-Barr virus (EBV)-encoded nuclear antigen EBNA1 is critical for the persistence of the viral episome in replicating EBV-transformed human B cells. Therefore, all EBV-induced tumors express this foreign antigen....
5.
Ehrhart E, Segarini P, Tsang M, Carroll A, Barcellos-Hoff M
FASEB J . 1997 Oct; 11(12):991-1002. PMID: 9337152
The biological activity of transforming growth factor beta1 (TGF-beta) is controlled by its secretion as a latent complex in which it is noncovalently associated with latency-associated peptide (LAP). Activation is...
6.
Zhu Y, Sun H, Tsang M, McMahel J, Grigsby S, Yin T, et al.
J Biol Chem . 1997 Aug; 272(34):21334-40. PMID: 9261146
Interleukin-9 receptor (IL-9R) complex consists of a ligand-specific alpha chain and IL-2R gamma chain. In this study, two regions in the cytoplasmic domain of human IL-9Ralpha were found to be...
7.
Graham G, Wilkinson P, Nibbs R, Lowe S, Kolset S, Parker A, et al.
EMBO J . 1996 Dec; 15(23):6506-15. PMID: 8978677
We have studied the role of proteoglycans in the function of Macrophage Inflammatory Protein-1 alpha (MIP-1alpha), a member of the proteoglycan binding chemokine family. Sequence and peptide analysis has identified...
8.
Qian S, Burmester J, Tsang M, Weatherbee J, Hinck A, Ohlsen D, et al.
J Biol Chem . 1996 Nov; 271(48):30656-62. PMID: 8940041
Transforming growth factor-beta (TGF-beta) isoforms have differential binding affinities for the TGF-beta type II receptor (TbetaRII). In most cells, TGF-beta1 and TGF-beta3 bind to TbetaRII with much higher affinity than...
9.
Hinck A, Archer S, Qian S, Roberts A, Sporn M, Weatherbee J, et al.
Biochemistry . 1996 Jul; 35(26):8517-34. PMID: 8679613
The three-dimensional solution structure of human transforming growth factor beta 1 (TGF-beta 1) has been determined using multinuclear magnetic resonance spectroscopy and a hybrid distance geometry/ simulated annealing algorithm. It...
10.
Bottinger E, Factor V, Tsang M, Weatherbee J, Kopp J, Qian S, et al.
Proc Natl Acad Sci U S A . 1996 Jun; 93(12):5877-82. PMID: 8650186
All three isoforms of transforming growth factors beta (TGF-betal, TGF-beta2, and TGF-beta3) are secreted as latent complexes and activated extracellularly, leading to the release of the mature cytokines from their...