M J Hooth
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Explore the profile of M J Hooth including associated specialties, affiliations and a list of published articles.
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14
Citations
78
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Recent Articles
1.
Singh B, Nyska A, Kissling G, Lieuallen W, Johansson S, Malarkey D, et al.
Toxicol Pathol
. 2010 Mar;
38(3):372-81.
PMID: 20233943
B6C3F1 mice chronically exposed to 3,3',4,4'-tetrachloroazobenzene (TCAB), a contaminant of dichloroaniline-derived herbicides, developed a number of neoplastic and nonneoplastic lesions, including carcinoma of the urinary tract. Groups of fifty male...
2.
Knudsen G, Cheng Y, Kuester R, Hooth M, Sipes I
Drug Metab Dispos
. 2009 Aug;
37(11):2171-7.
PMID: 19704025
Studies were conducted to characterize the effects of dose and route of administration on the disposition of 1-butyl-1-methylpyrrolidinium (BmPy-Cl) in male Fischer-344 rats. After a single oral administration of [(14)C]BmPy-Cl...
3.
Cheng Y, Wright S, Hooth M, Sipes I
Drug Metab Dispos
. 2009 Jan;
37(4):909-16.
PMID: 19171679
Studies were conducted to characterize the effect of dose and route of administration on the disposition of N-butylpyridinium chloride (NBuPy-Cl), an ionic liquid with solvent properties. Urine was the major...
4.
Stout M, Nyska A, Collins B, Witt K, Kissling G, Malarkey D, et al.
Food Chem Toxicol
. 2009 Jan;
47(4):729-33.
PMID: 19166900
Trivalent chromium (Cr(III)) has been proposed to be an essential element, which may increase sensitivity to insulin and thus participate in carbohydrate and lipid metabolism. Humans ingest Cr(III) both as...
5.
Hooth M, Sills R, Burka L, Haseman J, Witt K, Orzech D, et al.
Food Chem Toxicol
. 2004 Sep;
42(11):1757-68.
PMID: 15350673
trans-Cinnamaldehyde is a widely used natural ingredient that is added to foods and cosmetics as a flavoring and fragrance agent. Male and female F344/N rats and B6C3F(1) mice were exposed...
6.
George S, Wolf D, Brooks L, Bailey K, Hooth M, Nelson G
Cancer Lett
. 2004 Jan;
204(1):15-21.
PMID: 14744530
Disinfection of drinking water has been one of the greatest public health successes. Numerous halogenated disinfection by-products (DBPs) occur and chronic ingestion has been associated with an increased risk for...
7.
Hooth M, DeAngelo A, George M, Gaillard E, Travlos G, Boorman G, et al.
Toxicol Pathol
. 2001 Jun;
29(2):250-9.
PMID: 11421493
Chlorine dioxide (ClO2) is an effective drinking water disinfectant, but sodium chlorate (NaClO3) has been identified as a potentially harmful disinfection by-product. Studies were performed to describe the development of...
8.
Golubovskaya V, Filatov L, Behe C, Presnell S, Hooth M, Smith G, et al.
Mol Carcinog
. 1999 Apr;
24(3):209-17.
PMID: 10204805
Telomeres, which are specialized structures consisting of T2AG3 repeats and proteins at the ends of chromosomes, may be essential for genomic stability. To test whether telomere length maintenance preserves genomic...
9.
Hooth M, Coleman W, Presnell S, Borchert K, Grisham J, Smith G
Am J Pathol
. 1998 Dec;
153(6):1913-21.
PMID: 9846981
Several studies have shown that cultured rat liver epithelial cells transform spontaneously after chronic maintenance in a confluent state in vitro. In the present study, multiple independent lineages of low-passage...
10.
Presnell S, Hooth M, Borchert K, Coleman W, Grisham J, Smith G
Hepatology
. 1998 Oct;
28(5):1253-9.
PMID: 9794909
A model of spontaneous malignant transformation was used to evaluate the molecular changes that take place in WB-F344 rat liver epithelial cells during neoplastic transformation and tumorigenesis. A comparison of...