M I Cybulsky
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Explore the profile of M I Cybulsky including associated specialties, affiliations and a list of published articles.
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53
Citations
3359
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Recent Articles
1.
Dansky H, Barlow C, Lominska C, Sikes J, Kao C, Weinsaft J, et al.
Arterioscler Thromb Vasc Biol
. 2001 Oct;
21(10):1662-7.
PMID: 11597942
- Vascular cell adhesion molecule-1 (VCAM-1/Vcam1) is a cytokine-inducible member of the immunoglobulin gene superfamily that is expressed by arterial endothelial cells in regions predisposed to atherosclerosis and at borders...
2.
Griffiths E, Krawczyk C, Kong Y, Raab M, Hyduk S, Bouchard D, et al.
Science
. 2001 Sep;
293(5538):2260-3.
PMID: 11567140
The molecular adapter Fyb/Slap regulates signaling downstream of the T cell receptor (TCR), but whether it plays a positive or negative role is controversial. We demonstrate that Fyb/Slap-deficient T cells...
3.
Parr B, Cornish V, Cybulsky M, McMahon A
Dev Biol
. 2001 Sep;
237(2):324-32.
PMID: 11543617
Secreted Wnt proteins regulate many developmental processes in multicellular organisms. We have generated a targeted mutation in the mouse Wnt7b gene. Homozygous Wnt7b mutant mice die at midgestation stages as...
4.
Cybulsky M, Iiyama K, Li H, Zhu S, Chen M, Iiyama M, et al.
J Clin Invest
. 2001 May;
107(10):1255-62.
PMID: 11375415
VCAM-1 and ICAM-1 are endothelial adhesion molecules of the Ig gene superfamily that may participate in atherogenesis by promoting monocyte accumulation in the arterial intima. Both are expressed in regions...
5.
Chan J, Hyduk S, Cybulsky M
J Exp Med
. 2001 May;
193(10):1149-58.
PMID: 11369786
Chemoattractants and chemokines induce arrest of rolling monocytes during emigration from blood into tissues. In this study, we demonstrated that alpha4 integrin affinity for vascular cell adhesion molecule (VCAM)-1 was...
6.
Collins T, Cybulsky M
J Clin Invest
. 2001 Feb;
107(3):255-64.
PMID: 11160146
No abstract available.
7.
Chu Y, Heistad D, Cybulsky M, Davidson B
Arterioscler Thromb Vasc Biol
. 2001 Feb;
21(2):238-42.
PMID: 11156859
We have reported that adenovirus-mediated gene transfer is augmented in the endothelium of atherosclerotic blood vessels. We observed that vascular cell adhesion molecule-1 (VCAM-1) shares some homology with the coxsackievirus...
8.
Hajra L, Evans A, Chen M, Hyduk S, Collins T, Cybulsky M
Proc Natl Acad Sci U S A
. 2000 Aug;
97(16):9052-7.
PMID: 10922059
Atherosclerotic lesions form at distinct sites in the arterial tree, suggesting that hemodynamic forces influence the initiation of atherogenesis. If NF-kappaB plays a role in atherogenesis, then the activation of...
9.
McCaffrey T, Fu C, DU B, Eksinar S, Kent K, Bush Jr H, et al.
J Clin Invest
. 2000 Mar;
105(5):653-62.
PMID: 10712437
To understand the mRNA transcript profile in the human atherosclerotic lesion, RNA was prepared from the fibrous cap versus adjacent media of 13 patients undergoing carotid endarterectomy. cDNA expression arrays...
10.
Chan J, Hyduk S, Cybulsky M
J Immunol
. 2000 Jan;
164(2):746-53.
PMID: 10623819
Modulation of integrin affinity and/or avidity provides a regulatory mechanism by which leukocyte adhesion to endothelium is strengthened or weakened at different stages of emigration. In this study, we demonstrate...