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M I Cybulsky

Explore the profile of M I Cybulsky including associated specialties, affiliations and a list of published articles. Areas
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Articles 53
Citations 3359
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Recent Articles
11.
Cybulsky M, Lichtman A, Hajra L, Iiyama K
Clin Chim Acta . 1999 Oct; 286(1-2):207-18. PMID: 10511293
Functions of mononuclear leukocytes and endothelial cell leukocyte adhesion molecules in the formation of early atherosclerotic lesions is discussed. The main transgenic mouse models developed to study cholesterol metabolism and...
12.
Lichtman A, Clinton S, Iiyama K, Connelly P, Libby P, Cybulsky M
Arterioscler Thromb Vasc Biol . 1999 Aug; 19(8):1938-44. PMID: 10446074
Past studies of atherosclerosis in mice have used chow-based diets supplemented with cholesterol, lipid, and sodium cholate to overcome species resistance to lesion formation. Similar diets have been routinely used...
13.
Iiyama K, Hajra L, Iiyama M, Li H, DiChiara M, Medoff B, et al.
Circ Res . 1999 Jul; 85(2):199-207. PMID: 10417402
The recruitment of mononuclear leukocytes and formation of intimal macrophage-rich lesions at specific sites of the arterial tree are key events in atherogenesis. Inducible endothelial cell adhesion molecules may participate...
14.
Spragg D, Alford D, Greferath R, LARSEN C, Lee K, Gurtner G, et al.
Proc Natl Acad Sci U S A . 1997 Aug; 94(16):8795-800. PMID: 9238057
Endothelial-selective delivery of therapeutic agents, such as drugs or genes, would provide a useful tool for modifying vascular function in various disease states. A potential molecular target for such delivery...
15.
Friedrich C, Cybulsky M, Gutierrez-Ramos J
Eur J Immunol . 1996 Nov; 26(11):2773-80. PMID: 8921968
Binding of myeloid and lymphoid precursors to stromal cells in bone marrow has been suggested to be mediated through alpha 4 integrins (alpha 4) and vascular cell adhesion molecule-1 (VCAM-1)...
16.
Krejcy K, Schwarzacher S, FERBER W, Plesch C, Cybulsky M, Weidinger F
Atherosclerosis . 1996 Apr; 122(1):59-67. PMID: 8724112
Previous studies have demonstrated impaired endothelium-dependent vasodilation following balloon injury of the rabbit iliac artery, suggesting dysfunction of the regenerated endothelium. More recently, expression of vascular cell adhesion molecule-1 (VCAM-1)...
17.
Kiely J, Cybulsky M, Luscinskas F, Gimbrone Jr M
Arterioscler Thromb Vasc Biol . 1995 Aug; 15(8):1211-8. PMID: 7542999
An immunoconjugate was designed to target hirudin, a potent and specific inhibitor of thrombin, to the surface of activated endothelial cells. Hirudin was covalently cross-linked to the monoclonal antibody H18/7...
18.
Gimbrone Jr M, Cybulsky M, Kume N, Collins T, RESNICK N
Ann N Y Acad Sci . 1995 Jan; 748:122-31; discussion 131-2. PMID: 7535025
No abstract available.
19.
Walpola P, Gotlieb A, Cybulsky M, Langille B
Arterioscler Thromb Vasc Biol . 1995 Jan; 15(1):2-10. PMID: 7538423
Local shear stresses generated by blood flow exert direct mechanical effects on adhesion of circulating leukocytes to vascular endothelium, but their effects on expression of endothelial-leukocyte adhesion molecules have not...
20.
Gurtner G, Davis V, Li H, McCoy M, Sharpe A, Cybulsky M
Genes Dev . 1995 Jan; 9(1):1-14. PMID: 7530222
Vascular cell adhesion molecule-1 (VCAM-1) is expressed on vascular endothelium in a variety of inflammatory conditions and mediates leukocyte recruitment from blood into tissues. In this study we report a...