M Bissonnette
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Explore the profile of M Bissonnette including associated specialties, affiliations and a list of published articles.
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34
Citations
421
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Recent Articles
11.
Chen A, Davis B, Bissonnette M, Brasitus T
J Biol Chem
. 1999 Dec;
274(50):35505-13.
PMID: 10585423
1,25-Dihydroxyvitamin D(3) (1,25(OH)(2)D(3)) is a potential chemopreventive agent for human colon cancer. We have reported that 1,25(OH)(2)D(3) specifically activated protein kinase C-alpha (PKC-alpha) and also caused a reduction in proliferation...
12.
Sitrin M, Bissonnette M, Bolt M, Wali R, Khare S, Skarosi S, et al.
Steroids
. 1999 May;
64(1-2):137-42.
PMID: 10323682
Previous work from our laboratory demonstrated that 1,25(OH)2D3 rapidly stimulated hydrolysis of membrane polyphosphoinositides (PI) in rat colonocytes and in Caco-2 cells, generating the second messengers DAG and IP3. [Ca2+]i...
13.
Khare S, Bissonnette M, Wali R, Skarosi S, Boss G, Von Lintig F, et al.
Am J Physiol
. 1999 Apr;
276(4 Pt 1):G1005-15.
PMID: 10198345
In the accompanying paper [Khare et al., Am. J. Physiol. 276 (Gastrointest. Liver Physiol. 39): G993-G1004, 1999], activation of protein kinase C-alpha (PKC-alpha) was shown to be involved in the...
14.
Khare S, Bissonnette M, Wali R, Sitrin M, Brasitus T
Am J Physiol
. 1999 Apr;
276(4):G993-G1004.
PMID: 10198344
1,25-Dihydroxyvitamin D3 [1,25(OH)2D3] and 12-O-tetradecanoylphorbol 13-acetate (TPA) both activated phospholipase D (PLD) in Caco-2 cells. GF-109203x, an inhibitor of protein kinase C (PKC) isoforms, inhibited this activation by both of...
15.
Bolt M, Mailloux R, Rasenick M, Wali R, Skarosi S, Bissonnette M, et al.
Gastroenterology
. 1998 Dec;
115(6):1494-503.
PMID: 9834277
Background & Aims: Heterotrimeric G proteins are important in growth-regulating signal transduction. The aim of this study was to characterize the relative expression of G protein alpha subunits in rat...
16.
Wali R, Bissonnette M, Skarosi S, Khare S, Sitrin M, Brasitus T
Biochem Biophys Res Commun
. 1998 Sep;
250(1):48-52.
PMID: 9735329
Prior studies by our laboratory have shown that 1, 25-dihydroxyvitamin D3 activated PKC-alpha, but not PKC-delta, -epsilon, or -zeta, in normal rat colonocytes. In the present studies we demonstrate for...
17.
Brasitus T, Bissonnette M
Gastroenterology
. 1998 Jul;
115(1):225-7.
PMID: 9649481
No abstract available.
18.
Abraham C, Bissonnette M, Skarosi S, Hart J, Davidson N, Wali R, et al.
Cancer Res
. 1998 Mar;
58(5):1074-81.
PMID: 9500474
Previous studies have shown that PKC-alpha protein expression is decreased in sporadic human colon cancers, as well as in colonic tumors of rats induced by chemical carcinogens. To elucidate the...
19.
Abraham C, Skarosi S, Qin W, Bissonnette M, Brasitus T
Gastroenterology
. 1998 Mar;
114(3):503-9.
PMID: 9496940
Background & Aims: Caco-2 cells have been used extensively to elucidate events involved in intestinal cell proliferation and differentiation. Because individual isoforms of protein kinase C (PKC) and p21waf1, a...
20.
Khare S, Bolt M, Wali R, Skarosi S, Roy H, Niedziela S, et al.
J Clin Invest
. 1997 Apr;
99(8):1831-41.
PMID: 9109427
Our laboratory has previously demonstrated that 1,25-dihydroxyvitamin D3 (1,25[OH]2D3) rapidly stimulated polyphosphoinositide (PI) hydrolysis, raised intracellular Ca2+, and activated two Ca2+-dependent protein kinase C (PKC) isoforms, PKC-alpha and -betaII in...