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B P Frawley Jr

Explore the profile of B P Frawley Jr including associated specialties, affiliations and a list of published articles. Areas
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Citations 25
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1.
Wali R, Frawley Jr B, Hartmann S, Roy H, Khare S, Earnest D, et al.
Cancer Res . 1995 Nov; 55(22):5257-64. PMID: 7585585
Several lines of evidence from our laboratory and others indicate that epigenetic alterations in protein kinase C (PKC) are involved in colonic carcinogenesis in both man and experimental animals. Furthermore,...
2.
Roy H, Bissonnette M, Frawley Jr B, Wali R, Niedziela S, Earnest D, et al.
FEBS Lett . 1995 Jun; 366(2-3):143-5. PMID: 7789532
While nonsteroidal anti-inflammatory drugs have been shown to exert preventive effects against the development of colonic tumors in humans and in chemically-induced tumors in animal models, the mechanism(s) involved in...
3.
Bissonnette M, Tien X, Niedziela S, Hartmann S, Frawley Jr B, Roy H, et al.
Am J Physiol . 1994 Sep; 267(3 Pt 1):G465-75. PMID: 7943245
Our laboratory recently reported that 1,25-dihydroxyvitamin D3 [1,25(OH)2D3] rapidly increases the breakdown of membrane phosphoinositides, raises intracellular calcium concentration ([Ca2+]i), and translocates protein kinase C (PKC) from the cytosolic to...
4.
Frawley Jr B, Tien X, Hartmann S, Wali R, Niedziela S, Davidson N, et al.
Biochim Biophys Acta . 1994 Jun; 1222(2):301-5. PMID: 8031867
The present studies were undertaken to examine the expression of PKC isoforms within the nucleus of Caco-2 cells, a cell line widely used to investigate intestinal cell growth and differentiation,...