M Azim Surani
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Explore the profile of M Azim Surani including associated specialties, affiliations and a list of published articles.
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149
Citations
13111
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Recent Articles
21.
Sybirna A, Tang W, Pierson Smela M, Dietmann S, Gruhn W, Brosh R, et al.
Nat Commun
. 2020 Mar;
11(1):1282.
PMID: 32152282
PRDM14 is a crucial regulator of mouse primordial germ cells (mPGCs), epigenetic reprogramming and pluripotency, but its role in the evolutionarily divergent regulatory network of human PGCs (hPGCs) remains unclear....
22.
Wu B, Li L, Li B, Gao J, Chen Y, Wei M, et al.
Stem Cell Reports
. 2020 Feb;
14(2):241-255.
PMID: 32032551
Inhibitors of Mek1/2 and Gsk3β, known as 2i, and, together with leukemia inhibitory factor, enhance the derivation of embryonic stem cells (ESCs) and promote ground-state pluripotency (2i/L-ESCs). However, recent reports...
23.
Neupane J, Wong F, Surani M
Cell Res
. 2020 Jan;
30(2):103-104.
PMID: 31913357
No abstract available.
24.
Pierson Smela M, Sybirna A, Wong F, Surani M
Wellcome Open Res
. 2019 Oct;
4:122.
PMID: 31583280
Potentially novel regulators of early human germline development have been identified recently, including SOX15 and SOX17, both of which show specific expression in human primordial germ cells. SOX17 is now...
25.
Sybirna A, Wong F, Surani M
Curr Top Dev Biol
. 2019 Jun;
135:35-89.
PMID: 31155363
Primordial germ cells (PGCs) are embryonic precursors of sperm and egg that pass on genetic and epigenetic information from one generation to the next. In mammals, they are induced from...
26.
Ramos-Ibeas P, Sang F, Zhu Q, Tang W, Withey S, Klisch D, et al.
Nat Commun
. 2019 Feb;
10(1):500.
PMID: 30700715
High-resolution molecular programmes delineating the cellular foundations of mammalian embryogenesis have emerged recently. Similar analysis of human embryos is limited to pre-implantation stages, since early post-implantation embryos are largely inaccessible....
27.
Hackett J, Huang Y, Gunesdogan U, Gretarsson K, Kobayashi T, Surani M
Nat Commun
. 2018 Dec;
9(1):5328.
PMID: 30538240
Ufuk Günesdogan was incorrectly associated with Center for Genetic Analysis of Behaviour, National Institute for Physiological Sciences, 5-1 Higashiyama Myodaiji, Okazaki, Aichi 444-8787, Japan and Toshihiro Kobayashi was incorrectly associated...
28.
Penfold C, Sybirna A, Reid J, Huang Y, Wernisch L, Ghahramani Z, et al.
Bioinformatics
. 2018 Nov;
34(17):i1005-i1013.
PMID: 30423108
Motivation: A common class of behaviour encountered in the biological sciences involves branching and recombination. During branching, a statistical process bifurcates resulting in two or more potentially correlated processes that...
29.
Hackett J, Huang Y, Gunesdogan U, Gretarsson K, Kobayashi T, Surani M
Nat Commun
. 2018 Oct;
9(1):4292.
PMID: 30327475
Early mammalian development entails transit through naive pluripotency towards post-implantation epiblast, which subsequently gives rise to primordial germ cells (PGC), the founding germline population. To investigate these cell fate transitions,...
30.
Tischler J, Gruhn W, Reid J, Allgeyer E, Buettner F, Marr C, et al.
EMBO J
. 2018 Sep;
38(1).
PMID: 30257965
An intricate link is becoming apparent between metabolism and cellular identities. Here, we explore the basis for such a link in an model for early mouse embryonic development: from naïve...