M A Venkatachalam
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Explore the profile of M A Venkatachalam including associated specialties, affiliations and a list of published articles.
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99
Citations
2497
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Recent Articles
1.
Weinberg J, Bienholz A, Venkatachalam M
Cell Mol Life Sci
. 2016 Apr;
73(11-12):2285-308.
PMID: 27066896
The cytoprotective effects of glycine against cell death have been recognized for over 28 years. They are expressed in multiple cell types and injury settings that lead to necrosis, but...
2.
Singha P, Pandeswara S, Venkatachalam M, Saikumar P
Cell Death Dis
. 2013 Jan;
4:e457.
PMID: 23328664
Therapy resistance can be attributed to acquisition of anti-apoptotic mechanisms by the cancer cells. Therefore, developing approaches that trigger non-apoptotic cell death in cancer cells to compensate for apoptosis resistance...
3.
Shanmugasundaram K, Block K, Nayak B, Livi C, Venkatachalam M, Sudarshan S
Oncogene
. 2012 Jun;
32(16):2027-36.
PMID: 22733130
The cyclin-dependent kinase inhibitor p27 is a key regulator of cell-cycle progression. Its expression and localization are altered in several types of malignancies, which has prognostic significance in cancers such...
4.
Feldkamp T, Park J, Pasupulati R, Amora D, Roeser N, Venkatachalam M, et al.
Am J Physiol Renal Physiol
. 2009 Sep;
297(6):F1632-46.
PMID: 19741014
Development of the mitochondrial permeability transition (MPT) can importantly contribute to lethal cell injury from both necrosis and apoptosis, but its role varies considerably with both the type of cell...
5.
Kar R, Singha P, Venkatachalam M, Saikumar P
Oncogene
. 2009 May;
28(28):2556-68.
PMID: 19448671
Thiol reactive cyclopentenone prostaglandin, 15-deoxy-Delta(12,14)-prostaglandin J(2) (15d-PGJ2), induced a novel, nonapoptotic and microtubule-associated protein 1 light chain 3 (MAP1 LC3) dependent but nonautophagic form of cell death in colon, breast...
6.
Weinberg J, Venkatachalam M
J Clin Invest
. 2001 Nov;
108(9):1279-81.
PMID: 11696571
No abstract available.
7.
Nishiyama J, Yi X, Venkatachalam M, Dong Z
Biochem J
. 2001 Nov;
360(Pt 1):49-56.
PMID: 11695991
Caspase-9 is the apex caspase of the mitochondrial pathway of apoptosis, which plays a critical role in apoptotic initiation and progression. However, gene regulation of caspase-9 is largely unknown. This...
8.
Weinberg J, Venkatachalam M, Roeser N, Senter R, Nissim I
Am J Pathol
. 2001 Jun;
158(6):2153-64.
PMID: 11395393
Anaerobic mitochondrial metabolism of alpha-ketoglutarate and aspartate or alpha-ketoglutarate and malate can prevent and reverse severe mitochondrial dysfunction during reoxygenation after 60 minutes of hypoxia in kidney proximal tubules.(34) The...
9.
MIKHAILOV V, Mikhailova M, Pulkrabek D, Dong Z, Venkatachalam M, Saikumar P
J Biol Chem
. 2001 Mar;
276(21):18361-74.
PMID: 11279112
ATP depletion results in Bax translocation from cytosol to mitochondria and release of cytochrome c from mitochondria into cytosol in cultured kidney cells. Overexpression of Bcl-2 prevents cytochrome c release,...
10.
Dong Z, Venkatachalam M, Wang J, Patel Y, Saikumar P, Semenza G, et al.
J Biol Chem
. 2001 Mar;
276(22):18702-9.
PMID: 11278985
Hypoxia is a key determinant of tissue pathology during tumor development and organ ischemia. However, little is known regarding hypoxic regulation of genes that are directly involved in cell death...