M A Gacad
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Explore the profile of M A Gacad including associated specialties, affiliations and a list of published articles.
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Articles
22
Citations
459
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Recent Articles
11.
Specificity of steroid binding in New World primate B95-8 cells with a vitamin D-resistant phenotype
Gacad M, Adams J
Endocrinology
. 1992 Dec;
131(6):2581-7.
PMID: 1446602
We recently described the existence of a competitive binding component in vitamin D-resistant New World primate cells that has a relatively low affinity (Kd, approximately 10(-8) M) but high capacity...
12.
Gacad M, Adams J
J Clin Invest
. 1991 Mar;
87(3):996-1001.
PMID: 1847942
When assessed by 1,25-dihydroxyvitamin D3 (1,25(OH)2-D3)-receptor (VDR) binding analysis or 1,25(OH)2-D3-VDR-directed bioresponsiveness, cultured cells from some New World primates (platyrrhines) demonstrate a variable decrement in VDR when compared with Old...
13.
Adams J, Gacad M, Diz M, Nadler J
J Clin Endocrinol Metab
. 1990 Mar;
70(3):595-600.
PMID: 2106525
In the human granulomatous disease sarcoidosis hypercalcemia and/or hypercalciuria result from the endogenous overproduction of 1,25-dihydroxyvitamin D [1,25-(OH)2D] by the disease-activated macrophage. Unlike the renal 25-hydroxy-vitamin D (25OHD)-1-hydroxylase, normally the...
14.
Adams J, Fernandez M, Gacad M, Gill P, Endres D, Rasheed S, et al.
Blood
. 1989 Jan;
73(1):235-9.
PMID: 2910361
Fifteen patients with lymphoma and hypercalcemia (greater than or equal to 11.0 mg/dL) were identified by screening the serum chemistry profile obtained from patients upon admission to the Los Angeles...
15.
Adams J, Gacad M
J Clin Endocrinol Metab
. 1988 Jan;
66(1):224-9.
PMID: 2826527
High serum of 1,25-dihydroxyvitamin D3 [1,25-(OH)2D3] concentrations and target organ resistance to the hormone are characteristic findings in some New World primates (platyrrhines). We examined the abilities of cultural dermal...
16.
Adams J, Gacad M, Anders A, Endres D, Sharma O
Sarcoidosis
. 1986 Mar;
3(1):1-6.
PMID: 3033783
In an attempt to identify factors that may indicate which patients with sarcoidosis are likely to manifest a clinical abnormality in calcium homeostasis, we measured serum concentrations of calcium, angiotensin...
17.
Adams J, Gacad M, Singer F, Sharma O
Ann N Y Acad Sci
. 1986 Jan;
465:587-94.
PMID: 3460396
No abstract available.
18.
Adams J, Gacad M, Baker A, Kheun G, Rude R
Endocrinology
. 1985 Jun;
116(6):2523-7.
PMID: 3922744
We investigated the occurrence of 1,25-dihydroxyvitamin D3 [1,25-(OH)2D3]-resistant osteomalacia in the New World primate colony of Saguinus imperator at the Los Angeles Zoo. The mean serum concentration of 1,25-(OH)2D3 was...
19.
Adams J, Singer F, Gacad M, Sharma O, Hayes M, Vouros P, et al.
J Clin Endocrinol Metab
. 1985 May;
60(5):960-6.
PMID: 2984238
Hypercalcemia and hypercalciuria in sarcoidosis are thought to result from the endogenous overproduction of an active vitamin D metabolite. We employed primary cultures of pulmonary alveolar macrophages from two patients...
20.
Adams J, Gacad M
J Exp Med
. 1985 Apr;
161(4):755-65.
PMID: 3838552
We investigated the 1 alpha-hydroxylation of vitamin D3 sterols by cultured pulmonary alveolar macrophages (PAM) from patients with sarcoidosis with or without clinically abnormal calcium homeostasis. Like the naturally occurring...