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Lynda F Bonewald

Explore the profile of Lynda F Bonewald including associated specialties, affiliations and a list of published articles. Areas
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Articles 131
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Recent Articles
11.
Glorieux F, Bonewald L, Harvey N, van der Meulen M
Orphanet J Rare Dis . 2022 Feb; 17(1):30. PMID: 35101067
In recent years, much progress has been made in understanding the mechanisms of bone growth and development over a lifespan, including the crosstalk between muscle and bone, to achieve optimal...
12.
Pin F, Jones A, Huot J, Narasimhan A, Zimmers T, Bonewald L, et al.
J Bone Miner Res . 2021 Dec; 37(3):381-396. PMID: 34904285
Tumor- and bone-derived soluble factors have been proposed to participate in the alterations of skeletal muscle size and function in cachexia. We previously showed that mice bearing ovarian cancer (OvCa)...
13.
Pin F, Prideaux M, Bonewald L, Bonetto A
Curr Osteoporos Rep . 2021 Nov; 19(6):616-625. PMID: 34773212
Purpose Of Review: While the function of osteocytes under physiologic conditions is well defined, their role and involvement in cancer disease remains relatively unexplored, especially in a context of non-bone...
14.
Westendorf J, Bonewald L, Kiel D, Burtt N
Nat Rev Rheumatol . 2021 Oct; 18(1):1-2. PMID: 34686856
No abstract available.
15.
Toda Nakamura M, Zhang H, Guo D, Ueharu H, Pan H, Scott G, et al.
Genesis . 2021 Sep; 59(10):e23450. PMID: 34487426
Podoplanin, PDPN, is a mucin-type transmembrane glycoprotein widely expressed in many tissues, including lung, kidney, lymph nodes, and mineralized tissues. Its function is critical for lymphatic formation, differentiation of type...
16.
Pin F, Prideaux M, Huot J, Essex A, Plotkin L, Bonetto A, et al.
Cancer Lett . 2021 Jul; 520:80-90. PMID: 34233150
The effects of bone metastatic cancer on the skeleton are well described, whereas less is known regarding the effects of non-metastatic bone cancer on bone. Here we investigated the effects...
17.
Pin F, Bonewald L, Bonetto A
Exp Biol Med (Maywood) . 2021 Apr; 246(19):2118-2127. PMID: 33899538
Cancer-induced muscle wasting, i.e. cachexia, is associated with different types of cancer such as pancreatic, colorectal, lung, liver, gastric and esophageal. Cachexia affects prognosis and survival in cancer, and it...
18.
Ito N, Prideaux M, Wijenayaka A, Yang D, Ormsby R, Bonewald L, et al.
Calcif Tissue Int . 2021 Feb; 109(1):66-76. PMID: 33616712
Osteocyte produced fibroblast growth factor 23 (FGF23) is the key regulator of serum phosphate (Pi) homeostasis. The interplay between parathyroid hormone (PTH), FGF23 and other proteins that regulate FGF23 production...
19.
Prideaux M, Stern A, Bonewald L
Methods Mol Biol . 2020 Sep; 2221:3-13. PMID: 32979194
Osteocytes are thought to be the mechanosensors of bone by sensing mechanical loads imposed upon the bone and transmitting these signals to the other bone cells to initiate bone modeling...
20.
Robling A, Bonewald L
Annu Rev Physiol . 2020 Feb; 82:485-506. PMID: 32040934
Osteocytes are an ancient cell, appearing in fossilized skeletal remains of early fish and dinosaurs. Despite its relative high abundance, even in the context of nonskeletal cells, the osteocyte is...