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Lukasz Marczak

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Articles 97
Citations 1107
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Recent Articles
1.
Fochtman D, Marczak L, Pietrowska M, Wojakowska A
J Extracell Vesicles . 2024 Dec; 13(12):e70020. PMID: 39692094
Proteomic profiling of small extracellular vesicles (sEV) is a powerful tool for discovering biomarkers of various diseases. This process most often assisted by mass spectrometry (MS) usually lacks standardization and...
2.
Gawel M, Malecki P, Sliwiak J, Stepniewska M, Imiolczyk B, Czyrko-Horczak J, et al.
Chem Commun (Camb) . 2024 Sep; 60(81):11504-11507. PMID: 39230573
We report biochemical and structural studies on inhibiting bacterial -adenosyl-L-homocysteine hydrolase by transition metal cations. Our results revealed diverse molecular mechanisms of enzyme inactivation. Depending on the cation, the mechanism...
3.
Fochtman D, Wojakowska A, Marczak L
Postepy Biochem . 2024 Jul; 70(2):204-211. PMID: 39083469
Mass spectrometry (MS) as an analytical technique enables the identification and quantitative determination of proteins, metabolites, or lipids in a studied sample. However, this method has limitations regarding the number...
4.
Nolka-Szaszner M, Strugala A, Marczak L
Postepy Biochem . 2024 Jul; 70(2):212-222. PMID: 39083467
Mass spectrometry is an important tool in proteomic, metabolomic and lipidomic analysis. To fully use its potential, it is crucial to select and configure the appropriate analytical approach. For untargeted...
5.
Pietras P, Wasilewska-Burczyk A, Peplowska K, Marczak L, Tyczewska A, Grzywacz K
Int J Biol Macromol . 2024 May; 268(Pt 2):132004. PMID: 38697435
Ribosomes, intercellular macromolecules responsible for translation in the cell, are composed of RNAs and proteins. While rRNA makes the scaffold of the ribosome and directs the catalytic steps of protein...
6.
Wojakowska A, Marczak L, Zeman M, Chekan M, Zembala-Nozynska E, Polanski K, et al.
Front Oncol . 2024 Feb; 14:1323961. PMID: 38410100
Background: Neoadjuvant radiotherapy (neo-RT) is widely used in locally advanced rectal cancer (LARC) as a component of radical treatment. Despite the advantages of neo-RT, which typically improves outcomes in LARC...
7.
Litowczenko J, Wychowaniec J, Zaleski K, Marczak L, Edwards-Gayle C, Tadyszak K, et al.
Biomater Adv . 2023 Oct; 154:213653. PMID: 37862812
Topographical cues on materials can manipulate cellular fate, particularly for neural cells that respond well to such cues. Utilizing biomaterial surfaces with topographical features can effectively influence neuronal differentiation and...
8.
Grajzer M, Wiatrak B, Jawien P, Marczak L, Wojakowska A, Wiejak R, et al.
Foods . 2023 May; 12(9). PMID: 37174392
Wild strawberry L.) seed oil (WSO) recovered by two methods-cold pressing (CP) and extraction with supercritical carbon dioxide (SCOE)-taking into account the different extraction times, was characterized for its composition...
9.
Piasecki P, Wiatr K, Ruszkowski M, Marczak L, Trottier Y, Figiel M
Front Mol Neurosci . 2023 Apr; 16:1122308. PMID: 37033372
Spinocerebellar ataxia type 3 (SCA3/MJD) is a neurodegenerative disease caused by CAG expansion in mutant gene. The resulting PolyQ tract in mutant ataxin-3 protein is toxic to neurons and currently...
10.
Rybczynski J, Marczak L, Stobiecki M, Strugala A, Mikula A
Int J Mol Sci . 2022 Oct; 23(19). PMID: 36233080
The aim of this study was to demonstrate the metabolic profile of post-culture medium as an expression of cell suspension metabolic activity of the tree fern Sternb. The molecular profile...