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Lukas Steuernagel

Explore the profile of Lukas Steuernagel including associated specialties, affiliations and a list of published articles. Areas
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Articles 12
Citations 145
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11.
Vesting A, Jais A, Klemm P, Steuernagel L, Wienand P, Fog-Tonnesen M, et al.
Mol Metab . 2022 Nov; 66:101626. PMID: 36356831
Objective: Nonalcoholic fatty liver disease (NAFLD) ranges from steatosis to nonalcoholic steatohepatitis (NASH), which often progresses to hepatocellular carcinoma (HCC) through a largely undefined mechanism. NASH and HCC depend on...
12.
Gaziano I, Corneliussen S, Biglari N, Neuhaus R, Shen L, Sotelo-Hitschfeld T, et al.
JCI Insight . 2022 Nov; 7(21). PMID: 36345942
Dopamine acts on neurons in the arcuate nucleus (ARC) of the hypothalamus, which controls homeostatic feeding responses. Here we demonstrate a differential enrichment of dopamine receptor 1 (Drd1) expression in...
13.
Steuernagel L, Lam B, Klemm P, Dowsett G, Bauder C, Tadross J, et al.
Nat Metab . 2022 Oct; 4(10):1402-1419. PMID: 36266547
The hypothalamus plays a key role in coordinating fundamental body functions. Despite recent progress in single-cell technologies, a unified catalog and molecular characterization of the heterogeneous cell types and, specifically,...
14.
Porniece Kumar M, Cremer A, Klemm P, Steuernagel L, Sundaram S, Jais A, et al.
Nat Metab . 2021 Dec; 3(12):1662-1679. PMID: 34931084
Insulin acts on neurons and glial cells to regulate systemic glucose metabolism and feeding. However, the mechanisms of insulin access in discrete brain regions are incompletely defined. Here we show...
15.
Steuernagel L, Meckbach C, Heinrich F, Zeidler S, Schmitt A, Gultas M
PLoS One . 2019 May; 14(5):e0216475. PMID: 31095599
Transcription factors (TFs) are a special class of DNA-binding proteins that orchestrate gene transcription by recruiting other TFs, co-activators or co-repressors. Their combinatorial interplay in higher organisms maintains homeostasis and...