Brian Y H Lam
Overview
Explore the profile of Brian Y H Lam including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
42
Citations
1278
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Wallis N, McClellan A, Morseburg A, Kentistou K, Jamaluddin A, Dowsett G, et al.
Science
. 2025 Mar;
:eads2145.
PMID: 40048553
Obesity is a heritable disease, but its genetic basis is incompletely understood. Canine population history facilitates trait mapping. We performed a canine genome-wide association study for body condition score, a...
2.
Jia R, Lockhart S, Lam B, Zhao Y, Kentistou K, Gardner E, et al.
J Clin Endocrinol Metab
. 2025 Mar;
PMID: 40036808
Objectives: Clinical case-based studies have identified rare pathogenic variants in several genes as causes of severe early-onset obesity, but their penetrance and interaction with polygenic susceptibility in the general population...
3.
Tadross J, Steuernagel L, Dowsett G, Kentistou K, Lundh S, Porniece M, et al.
Nature
. 2025 Feb;
639(8054):E17.
PMID: 40000749
No abstract available.
4.
Simonds S, Pryor J, Lam B, Dowsett G, Mustafa T, Munder A, et al.
Cell Rep Med
. 2025 Feb;
6(2):101936.
PMID: 39914386
Amphetamine (AMPH) exerts metabolic and cardiovascular effects. The central melanocortin system is a key regulator of both metabolic and cardiovascular functions. Here, we show that the melanocortin system partially mediates...
5.
Tadross J, Steuernagel L, Dowsett G, Kentistou K, Lundh S, Porniece M, et al.
Nature
. 2025 Feb;
PMID: 39910307
The hypothalamus is a brain region that plays a key role in coordinating fundamental biological functions. However, our understanding of the underlying cellular components and neurocircuitries have, until recently, emerged...
6.
Lockhart S, Muso M, Zvetkova I, Lam B, Ferrari A, Schoenmakers E, et al.
Nat Metab
. 2024 Sep;
6(10):1922-1938.
PMID: 39322746
Liver X receptor-α (LXRα) regulates cellular cholesterol abundance and potently activates hepatic lipogenesis. Here we show that at least 1 in 450 people in the UK Biobank carry functionally impaired...
7.
Sandovici I, Fernandez-Twinn D, Campbell N, Cooper W, Sekita Y, Zvetkova I, et al.
Cell Rep
. 2024 Sep;
43(9):114750.
PMID: 39283743
Mir483 is a conserved and highly expressed microRNA in placental mammals, embedded within the Igf2 gene. Its expression is dysregulated in a number of human diseases, including metabolic disorders and...
8.
Sam A, Buckley A, Lam B, Bewick G, Bech P, Meeran K, et al.
Diabetes Metab Res Rev
. 2024 Jun;
40(5):e3829.
PMID: 38850100
Aims: Pancreatic polypeptide (PP) is elevated in people with vascular risk factors such as type 2 diabetes or increased visceral fat. We investigated potential relationships between PP and microvascular and...
9.
Leeson-Payne A, Iyinikkel J, Malcolm C, Lam B, Sommer N, Dowsett G, et al.
Cell Metab
. 2024 Apr;
36(5):1076-1087.e4.
PMID: 38653246
Approximately 1 in 4 people worldwide have non-alcoholic fatty liver disease (NAFLD); however, there are currently no medications to treat this condition. This study investigated the role of adiposity-associated orphan...
10.
Lopez-Tello J, Yong H, Sandovici I, Dowsett G, Christoforou E, Salazar-Petres E, et al.
Cell Metab
. 2023 Jul;
35(7):1195-1208.e6.
PMID: 37437545
Maternal-offspring interactions in mammals involve both cooperation and conflict. The fetus has evolved ways to manipulate maternal physiology to enhance placental nutrient transfer, but the mechanisms involved remain unclear. The...