F Thomas Wunderlich
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Explore the profile of F Thomas Wunderlich including associated specialties, affiliations and a list of published articles.
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90
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5848
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Recent Articles
1.
Izawa S, Fusca D, Jiang H, Heilinger C, Hausen A, Wunderlich F, et al.
Cell Rep
. 2025 Feb;
44(2):115277.
PMID: 39946231
Orexin/hypocretin receptor type 2 (Ox2R), which is widely expressed in the brain, receives orexin signals and modulates sleep and metabolism. Ox2R selective agonists are currently under clinical trials for narcolepsy...
2.
Huschet L, Kliem F, Wienand P, Wunderlich C, Ribeiro A, Bustos-Martinez I, et al.
Life Sci Alliance
. 2024 Dec;
8(3).
PMID: 39667914
Subcellular fractionation allows for the investigation of compartmentalized processes in individual cellular organelles. Nuclear enrichment methods commonly employ the use of density gradients combined with ultracentrifugation for freshly isolated tissues....
3.
Mulet I, Grueso-Cortina C, Cortes-Cano M, Gerovska D, Wu G, Iakab S, et al.
Nat Commun
. 2024 Nov;
15(1):9749.
PMID: 39557858
TET-family members play a critical role in cell fate commitment. Indeed, TET3 is essential to postnatal development due to yet unknown reasons. To define TET3 function in cell differentiation, we...
4.
Dodt S, Widdershooven N, Dreisow M, Weiher L, Steuernagel L, Wunderlich F, et al.
Nat Commun
. 2024 Jun;
15(1):5439.
PMID: 38937485
Efficient control of feeding behavior requires the coordinated adjustment of complex motivational and affective neurocircuits. Neuropeptides from energy-sensing hypothalamic neurons are potent feeding modulators, but how these endogenous signals shape...
5.
Henschke S, Nolte H, Magoley J, Kleele T, Brandt C, Hausen A, et al.
Science
. 2024 Apr;
384(6694):438-446.
PMID: 38662831
Liver mitochondria play a central role in metabolic adaptations to changing nutritional states, yet their dynamic regulation upon anticipated changes in nutrient availability has remained unaddressed. Here, we found that...
6.
Ackermann J, Arndt L, Froba J, Lindhorst A, Glass M, Kirstein M, et al.
Front Immunol
. 2024 Mar;
15:1201439.
PMID: 38482013
Introduction: Obesity is associated with chronic low-grade inflammation of adipose tissue (AT) and an increase of AT macrophages (ATMs) that is linked to the onset of type 2 diabetes. We...
7.
Vossen C, Schmidt P, Wunderlich C, Mittenbuhler M, Tapken C, Wienand P, et al.
Cells
. 2024 Jan;
13(1).
PMID: 38201306
Enteroendocrine cells (EECs) constitute only a small proportion of -expressing intestinal epithelial cells (IECs) of the gastrointestinal tract; yet, in sum, they build the largest endocrine organ of the body,...
8.
Peil J, Vossen C, Bock F, Clahsen T, Schiller P, Heindl L, et al.
J Immunol
. 2023 Dec;
212(3):487-499.
PMID: 38099710
Angiogenesis and immune protection are essential at the onset of tumorigenesis. Angiogenesis serves to nourish the tumor, and prevention of immune defenses, for example, by dendritic cells (DCs), allows tumor...
9.
Cox E, El-Behi M, Ries S, Vogt J, Kohlhaas V, Michna T, et al.
Cell Rep
. 2023 Apr;
42(4):112378.
PMID: 37060566
The signals controlling marginal zone (MZ) and follicular (FO) B cell development remain incompletely understood. Here, we show that AKT orchestrates MZ B cell formation in mice and humans. Genetic...
10.
Nagao H, Cai W, Brandao B, Wewer Albrechtsen N, Steger M, Gattu A, et al.
J Clin Invest
. 2022 Dec;
133(4).
PMID: 36548088
Insulin and IGF-1 receptors (IR and IGF1R) are highly homologous and share similar signaling systems, but each has a unique physiological role, with IR primarily regulating metabolic homeostasis and IGF1R...