Lukas Lacina
Overview
Explore the profile of Lukas Lacina including associated specialties, affiliations and a list of published articles.
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55
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1020
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Recent Articles
1.
Pfeiferova L, Spanko M, Sachova J, Hradilova M, Pienta K, Valach J, et al.
Histochem Cell Biol
. 2025 Mar;
163(1):38.
PMID: 40063181
Fibroblasts, the most abundant cell type in the human body, play crucial roles in biological processes such as inflammation and cancer progression. They originate from the mesoderm or neural-crest-derived ectomesenchyme....
2.
Lacina L, Kolar M, Pfeiferova L, Gal P, Smetana Jr K
Front Immunol
. 2024 Dec;
15:1403570.
PMID: 39676864
Wound healing represents a complex and evolutionarily conserved process across vertebrates, encompassing a series of life-rescuing events. The healing process runs in three main phases: inflammation, proliferation, and maturation/remodelling. While...
3.
Sindelka R, Naraine R, Abaffy P, Zucha D, Kraus D, Netusil J, et al.
Genome Biol
. 2024 Oct;
25(1):251.
PMID: 39350302
Background: Embryos are regeneration and wound healing masters. They rapidly close wounds and scarlessly remodel and regenerate injured tissue. Regeneration has been extensively studied in many animal models using new...
4.
Groza Y, Lacina L, Kuchar M, Raskova Kafkova L, Zachova K, Janouskova O, et al.
Cell Commun Signal
. 2024 May;
22(1):261.
PMID: 38715108
Background: Interleukin-6 (IL-6) is a multifunctional cytokine that controls the immune response, and its role has been described in the development of autoimmune diseases. Signaling via its cognate IL-6 receptor...
5.
Prochazka V, Lacina L, Smetana Jr K, Svoboda M, Skrivanova K, Benovska M, et al.
World J Surg Oncol
. 2023 Dec;
21(1):384.
PMID: 38098074
Background: The aim of this prospective study was to evaluate the role of serum IL-6 as a potential predictive biomarker of postoperative complications (POC) in elective colorectal surgery. Method: A...
6.
Urban L, Novak S, Coma M, Dvorankova B, Lacina L, Sachova J, et al.
Oncol Rep
. 2023 Nov;
51(1).
PMID: 37975220
Breast cancer is the most frequently diagnosed cancer in women worldwide. Although dramatically increased survival rates of early diagnosed cases have been observed, late diagnosed patients and metastatic cancer may...
7.
Taborska P, Lukac P, Stakheev D, Rajsiglova L, Kalkusova K, Strnadova K, et al.
Sci Rep
. 2023 Nov;
13(1):19079.
PMID: 37925511
Soft tissue sarcomas are aggressive mesenchymal-origin malignancies. Undifferentiated pleomorphic sarcoma (UPS) belongs to the aggressive, high-grade, and least characterized sarcoma subtype, affecting multiple tissues and metastasizing to many organs. The...
8.
Kejik Z, Koubkova N, Krcova L, Sykora D, Abramenko N, Vesela K, et al.
Bioorg Chem
. 2023 Sep;
141:106816.
PMID: 37716274
Pentamethinium indolium salts are promising fluorescence probes and anticancer agents with high mitochondrial selectivity. We synthesized two indolium pentamethinium salts: a cyclic form with quinoxaline directly incorporated in the pentamethinium...
9.
Urban L, Coma M, Lacina L, Szabo P, Sabova J, Urban T, et al.
Histochem Cell Biol
. 2023 Sep;
160(6):541-554.
PMID: 37707642
Identification of therapeutic targets for treating fibrotic diseases and cancer remains challenging. Our study aimed to investigate the effects of TGF-β1 and TGF-β3 on myofibroblast differentiation and extracellular matrix deposition...
10.
Mandys V, Popov A, Gurlich R, Havranek J, Pfeiferova L, Kolar M, et al.
Int J Mol Sci
. 2023 Feb;
24(4).
PMID: 36835029
Therapy for pancreatic ductal adenocarcinoma remains challenging, and the chances of a complete cure are very limited. As in other types of cancer, the expression and role of miRNAs in...