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Michal Kolar

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Articles 113
Citations 1354
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Recent Articles
1.
Pfeiferova L, Spanko M, Sachova J, Hradilova M, Pienta K, Valach J, et al.
Histochem Cell Biol . 2025 Mar; 163(1):38. PMID: 40063181
Fibroblasts, the most abundant cell type in the human body, play crucial roles in biological processes such as inflammation and cancer progression. They originate from the mesoderm or neural-crest-derived ectomesenchyme....
2.
Zimmann F, McNicoll F, Thakur P, Blazikova M, Kubovciak J, Hernandez Canas M, et al.
Cell Mol Life Sci . 2025 Mar; 82(1):103. PMID: 40045025
Retinitis pigmentosa (RP) is a hereditary disorder caused by mutations in more than 70 different genes including those that encode proteins important for pre-mRNA splicing. Most RP-associated mutations in splicing...
3.
Lacina L, Kolar M, Pfeiferova L, Gal P, Smetana Jr K
Front Immunol . 2024 Dec; 15:1403570. PMID: 39676864
Wound healing represents a complex and evolutionarily conserved process across vertebrates, encompassing a series of life-rescuing events. The healing process runs in three main phases: inflammation, proliferation, and maturation/remodelling. While...
4.
Miladinovic A, Antiga L, Venit T, Bayona-Hernandez A, cervenka J, Labala R, et al.
Adv Biol Regul . 2024 Dec; 95:101069. PMID: 39648081
The liquid-liquid phase separation in the cell nucleus regulates various processes such as gene regulation and transcription control, chromatin organization, and DNA repair. A plethora of proteins and RNAs contribute...
5.
Reblova M, Nekvindova J, Kolarik M, Jurjevic Z, Kolar M, Hubka V
MycoKeys . 2024 Dec; 110:319-360. PMID: 39619666
In this study, we assessed the phylogenetic relationships among members of and the morphologically similar genus , currently classified within the Sordariomycetes. Our phylogenetic analyses, utilising three and five gene...
6.
Nevorankova P, Sulcova M, Kavkova M, Zimcik D, Balkova S, Peleskova K, et al.
Sci Rep . 2024 Aug; 14(1):18212. PMID: 39107332
Mammalian dentition exhibits distinct heterodonty, with more simple teeth located in the anterior area of the jaw and more complex teeth situated posteriorly. While some region-specific differences in signalling have...
7.
Janeckova L, Stastna M, Hrckulak D, Berkova L, Kubovciak J, Onhajzer J, et al.
bioRxiv . 2024 Jul; PMID: 39026783
The single-layer epithelium of the gastrointestinal tract is a dynamically renewing tissue that ensures nutrient absorption, secretory and barrier functions and is involved in immune responses. The basis for this...
8.
Gbelcova H, Rimpelova S, Jariabkova A, Macasek P, Priscakova P, Ruml T, et al.
Sci Rep . 2024 May; 14(1):11830. PMID: 38782983
Statins, the drugs used for the treatment of hypercholesterolemia, have come into the spotlight not only as chemoadjuvants, but also as potential stem cell modulators in the context of regenerative...
9.
Tykvartova T, Miklovic M, Kotrc M, Skaroupkova P, Kazdova L, Trnovska J, et al.
Pharmacol Res Perspect . 2024 Jan; 12(1):e1172. PMID: 38284173
While phosphodiesterase-5 inhibition (PED5i) may prevent hypertrophy and failure in pressure-overloaded heart in an experimental model, the impact of PDE5i on volume-overload (VO)-induced hypertrophy is unknown. It is also unclear...
10.
Pospisil J, Schwarz M, Zikova A, Vitovska D, Hradilova M, Kolar M, et al.
Commun Biol . 2024 Jan; 7(1):46. PMID: 38184746
σ factors are considered as positive regulators of gene expression. Here we reveal the opposite, inhibitory role of these proteins. We used a combination of molecular biology methods and computational...