Lukas Lacina
Overview
Explore the profile of Lukas Lacina including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
55
Citations
1020
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
11.
Tesarova M, Peterkova L, Stastna M, Kolar M, Lacina L, Smetana Jr K, et al.
Biomedicines
. 2023 Jan;
11(1).
PMID: 36672540
Vestibular schwannoma is the most common benign neoplasm of the cerebellopontine angle. It arises from Schwann cells of the vestibular nerve. The first symptoms of vestibular schwannoma include hearing loss,...
12.
Raskova M, Lacina L, Kejik Z, Venhauerova A, Skalickova M, Kolar M, et al.
Cells
. 2022 Nov;
11(22).
PMID: 36429126
Interleukin 6 (IL-6) belongs to a broad class of cytokines involved in the regulation of various homeostatic and pathological processes. These activities range from regulating embryonic development, wound healing and...
13.
Talianova V, Kejik Z, Kaplanek R, Vesela K, Abramenko N, Lacina L, et al.
Pharmaceutics
. 2022 Aug;
14(8).
PMID: 36015338
IL-6 signaling is involved in the pathogenesis of a number of serious diseases, including chronic inflammation and cancer. Targeting of IL-6 receptor (IL-6R) by small molecules is therefore an intensively...
14.
Gal P, Brabek J, Holub M, Jakubek M, Sedo A, Lacina L, et al.
Histochem Cell Biol
. 2022 Jul;
158(5):415-434.
PMID: 35867145
Recent evidence indicates that targeting IL-6 provides broad therapeutic approaches to several diseases. In patients with cancer, autoimmune diseases, severe respiratory infections [e.g. coronavirus disease 2019 (COVID-19)] and wound healing,...
15.
Vokurka M, Lacina L, Brabek J, Kolar M, Ng Y, Smetana Jr K
Int J Mol Sci
. 2022 Jan;
23(2).
PMID: 35055153
Cancer-associated fibroblasts (CAFs) are an essential component of the tumour microenvironment. They represent a heterogeneous group of cells that are under the control of cancer cells and can reversely influence...
16.
Strnadova K, Pfeiferova L, Prikryl P, Dvorankova B, Vlcak E, Frydlova J, et al.
Histochem Cell Biol
. 2021 Nov;
157(2):153-172.
PMID: 34837514
The incidence of cutaneous malignant melanoma is increasing worldwide. While the treatment of initial stages of the disease is simple, the advanced disease frequently remains fatal despite novel therapeutic options...
17.
Spanko M, Strnadova K, Pavlicek A, Szabo P, Kodet O, Valach J, et al.
Int J Mol Sci
. 2021 Oct;
22(20).
PMID: 34681685
Interleukin-6 (IL-6) is a highly potent cytokine involved in multiple biological processes. It was previously reported to play a distinct role in inflammation, autoimmune and psychiatric disorders, ageing and various...
18.
Kodet O, Nemejcova K, Strnadova K, Havlinova A, Dundr P, Krajsova I, et al.
Int J Mol Sci
. 2021 Jul;
22(13).
PMID: 34281259
Therapy targeting immune checkpoints represents an integral part of the treatment for patients suffering from advanced melanoma. However, the mechanisms of resistance are responsible for a lower therapeutic outcome than...
19.
Abramenko N, Vellieux F, Tesarova P, Kejik Z, Kaplanek R, Lacina L, et al.
Int J Mol Sci
. 2021 Jul;
22(12).
PMID: 34207220
COVID-19 is a pandemic respiratory disease caused by the SARS-CoV-2 coronavirus. The worldwide epidemiologic data showed higher mortality in males compared to females, suggesting a hypothesis about the protective effect...
20.
Novak S, Kolar M, Szabo A, Vernerova Z, Lacina L, Strnad H, et al.
Cancer Genomics Proteomics
. 2021 Apr;
18(3):221-243.
PMID: 33893076
Background/aim: Pancreatic ductal adenocarcinoma (PDAC) still represents one of the most aggressive cancers. Understanding of the epithelial-mesenchymal crosstalk as a crucial part of the tumor microenvironment should pave the way...