Lukas Karbacher
Overview
Explore the profile of Lukas Karbacher including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
156
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Recent Articles
1.
Herdy J, Traxler L, Agarwal R, Karbacher L, Schlachetzki J, Boehnke L, et al.
Cell Stem Cell
. 2022 Dec;
29(12):1637-1652.e6.
PMID: 36459967
The concept of senescence as a phenomenon limited to proliferating cells has been challenged by growing evidence of senescence-like features in terminally differentiated cells, including neurons. The persistence of senescent...
2.
Zhou-Yang L, Eichhorner S, Karbacher L, Bohnke L, Traxler L, Mertens J
Methods Mol Biol
. 2021 Jul;
2352:73-96.
PMID: 34324181
Progressive aging is a physiological process that represents a central risk factor for the development of several human age-associated chronic diseases, including neurodegenerative diseases. A major focus in biomedical research...
3.
Mertens J, Herdy J, Traxler L, Schafer S, Schlachetzki J, Bohnke L, et al.
Cell Stem Cell
. 2021 Apr;
28(9):1533-1548.e6.
PMID: 33910058
Sporadic Alzheimer's disease (AD) exclusively affects elderly people. Using direct conversion of AD patient fibroblasts into induced neurons (iNs), we generated an age-equivalent neuronal model. AD patient-derived iNs exhibit strong...
4.
Herdy J, Karbacher L, Mertens J
Cell Stem Cell
. 2021 Jan;
28(1):1-2.
PMID: 33417865
Direct cell fate conversion of human somatic cells into induced neurons (iNs) is often regarded as a highly concerted one-step process. In this issue of Cell Stem Cell, Cates et ...