Lukas J A C Hawinkels
Overview
Explore the profile of Lukas J A C Hawinkels including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
65
Citations
2267
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Mateusiak L, Hakuno S, de Jonge-Muller E, Floru S, Sier C, Hawinkels L, et al.
Eur J Surg Oncol
. 2025 Jan;
51(3):109537.
PMID: 39753054
Background: Fluorescence molecular imaging, a potent and non-invasive technique, has become indispensable in medicine for visualizing molecular processes. In surgical oncology, it aids treatment by allowing visualization of tumor cells...
2.
de Jong M, Slingerland M, Hawinkels L, Nielsen M, Crobach A, de Jonge-Muller E, et al.
Fam Cancer
. 2024 Dec;
24(1):11.
PMID: 39630202
Nephrotic syndrome is a common clinical presentation of glomerulopathy. A glomerulopathy as a paraneoplastic manifestation caused by underlying malignancy is rare. In patients with a solid tumor, membranous nephropathy is...
3.
Biomarker screen for efficacy of oncolytic virotherapy in patient-derived pancreatic cancer cultures
Schafer T, Knol L, Haas F, Hartley A, Pernickel S, Jady A, et al.
EBioMedicine
. 2024 Jun;
105:105219.
PMID: 38941955
Background: Pancreatic ductal adenocarcinoma (PDAC) is a tumour entity with unmet medical need. To assess the therapeutic potential of oncolytic virotherapy (OVT) against PDAC, different oncolytic viruses (OVs) are currently...
4.
Abudukelimu S, de Miranda N, Hawinkels L
Cell Mol Gastroenterol Hepatol
. 2024 Feb;
17(5):821-826.
PMID: 38307492
Cancer-associated fibroblasts (CAFs) are an abundant component of the tumor microenvironment and have been shown to possess critical functions in tumor progression. Although their roles predominantly have been described as...
5.
Luk S, Schoppmeyer R, Ijsselsteijn M, Somarakis A, Acem I, Remst D, et al.
Cancer Immunol Res
. 2023 Sep;
11(11):1480-1492.
PMID: 37695550
Cancers evade T-cell immunity by several mechanisms such as secretion of anti-inflammatory cytokines, down regulation of antigen presentation machinery, upregulation of immune checkpoint molecules, and exclusion of T cells from...
6.
Hakuno S, Janson S, Trietsch M, de Graaf M, de Jonge-Muller E, Crobach S, et al.
Front Med (Lausanne)
. 2023 Jul;
10:1112573.
PMID: 37396898
Despite the fact that the role of endoglin on endothelial cells has been extensively described, its expression and biological role on (epithelial) cancer cells is still debatable. Especially its function...
7.
de Jong L, Boussallami S, Sanchez-Lopez E, Giera M, Tushuizen M, Hoekstra M, et al.
Front Pharmacol
. 2023 Jun;
14:1201906.
PMID: 37361233
Pharmacogenetics-informed drug prescribing is increasingly applied in clinical practice. Typically, drug metabolizing phenotypes are determined based on genetic test results, whereupon dosage or drugs are adjusted. Drug-drug-interactions (DDIs) caused by...
8.
Stouten I, van Montfoort N, Hawinkels L
Int J Mol Sci
. 2023 May;
24(10).
PMID: 37240052
The lack of response to therapy in pancreatic ductal adenocarcinoma (PDAC) patients has contributed to PDAC having one of the lowest survival rates of all cancer types. The poor survival...
9.
Dang H, Harryvan T, Liao C, Danen E, Spalburg V, Kielbasa S, et al.
Cell Mol Gastroenterol Hepatol
. 2023 Apr;
16(1):107-131.
PMID: 37085135
Background & Aims: Improving clinical management of early stage colorectal cancers (T1CRCs) requires a better understanding of their underlying biology. Accumulating evidence shows that cancer-associated fibroblasts (CAFs) are important determinants...
10.
Drexler S, Cai C, Hartmann A, Moch D, Gaitantzi H, Ney T, et al.
Mol Cell Endocrinol
. 2023 Apr;
570:111934.
PMID: 37085108
Bone morphogenetic protein (BMP)-9, a member of the TGFβ-family of cytokines, is believed to be mainly produced in the liver. The serum levels of BMP-9 were reported to be reduced...