Lukas J A C Hawinkels
Overview
Explore the profile of Lukas J A C Hawinkels including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
65
Citations
2267
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
11.
Intertumoral Differences Dictate the Outcome of TGF-β Blockade on the Efficacy of Viro-Immunotherapy
Groeneveldt C, van Ginkel J, Kinderman P, Sluijter M, Griffioen L, Labrie C, et al.
Cancer Res Commun
. 2023 Mar;
3(2):325-337.
PMID: 36860656
Significance: Blockade of the pleiotropic molecule TGF-β can both improve and impair the efficacy of viro-immunotherapy, depending on the tumor model. While TGF-β blockade antagonized Reo&CD3-bsAb combination therapy in the...
12.
Loveikyte R, Bourgonje A, van der Reijden J, Bulthuis M, Hawinkels L, Visschedijk M, et al.
Inflamm Bowel Dis
. 2023 Feb;
29(8):1272-1284.
PMID: 36748574
Background: Hepcidin, the systemic iron regulator, could be critical in differentiating iron deficiency (ID) from functional iron restriction in inflammatory bowel disease (IBD). We assessed hepcidin as a diagnostic ID...
13.
Zhou Z, Ouboter L, Peeters K, Hawinkels L, Holman F, Pascutti M, et al.
J Clin Med
. 2023 Jan;
12(2).
PMID: 36675403
Perianal fistulas are defined as pathological connections between the anorectal canal and the perianal skin. Most perianal fistulas are cryptoglandular fistulas, which are thought to originate from infected anal glands....
14.
Vuijk F, Kleiburg F, Noortman W, Heijmen L, Feshtali Shahbazi S, van Velden F, et al.
Cancers (Basel)
. 2022 Dec;
14(24).
PMID: 36551695
Current imaging modalities frequently misjudge disease stage in colorectal, gastric and pancreatic cancer. As treatment decisions are dependent on disease stage, incorrect staging has serious consequences. Previous preclinical research and...
15.
Roelands J, van der Ploeg M, Ijsselsteijn M, Dang H, Boonstra J, Hardwick J, et al.
Gut
. 2022 Nov;
72(7):1326-1339.
PMID: 36442992
Objective: Biological insights into the stepwise development and progression of colorectal cancer (CRC) are imperative to develop tailored approaches for early detection and optimal clinical management of this disease. Here,...
16.
Zhou Z, Plug L, Patente T, de Jonge-Muller E, Elmagd A, van der Meulen-de Jong A, et al.
Front Immunol
. 2022 Nov;
13:966067.
PMID: 36405760
Inflammatory bowel disease (IBD) is a chronic relapsing inflammation of the intestinal tract with currently not well-understood pathogenesis. In addition to the involvement of immune cells, increasing studies show an...
17.
Barnhoorn M, van der Meulen-de Jong A, Schrama E, Plug L, Verspaget H, Fibbe W, et al.
Stem Cells Transl Med
. 2022 Aug;
11(9):932-945.
PMID: 35984079
Locally applied mesenchymal stromal cells (MSCs) have the capacity to promote the healing of perianal fistulas in Crohn's disease (CD) and are under clinical development for the treatment of proctitis...
18.
Harryvan T, Golo M, Dam N, Schoonderwoerd M, Farshadi E, Hornsveld M, et al.
Cancer Gene Ther
. 2022 Jul;
29(12):1918-1929.
PMID: 35869278
Gastrointestinal (GI) cancers are characterized by extensive tumor stroma that both promotes tumor progression and acts as a physical barrier for adjacent tumor cells, limiting the effect of current treatment...
19.
Hakuno S, Michiels E, Kuhlemaijer E, Rooman I, Hawinkels L, Slingerland M
Int J Mol Sci
. 2022 Mar;
23(6).
PMID: 35328567
Cancers affecting the gastrointestinal system are highly prevalent and their incidence is still increasing. Among them, gastric and pancreatic cancers have a dismal prognosis (survival of 5-20%) and are defined...
20.
Kumar S, Schoonderwoerd M, Kroonen J, de Graaf I, Sluijter M, Ruano D, et al.
Gut
. 2022 Jan;
71(11):2266-2283.
PMID: 35074907
Objective: Pancreatic ductal adenocarcinoma (PDAC) has the characteristics of high-density desmoplastic stroma, a distinctive immunosuppressive microenvironment and is profoundly resistant to all forms of chemotherapy and immunotherapy, leading to a...