Familial Cancer
Overview
Familial Cancer is a peer-reviewed journal dedicated to advancing the understanding and management of hereditary cancer syndromes. It publishes high-quality research articles, reviews, and case reports that explore the genetic, clinical, and psychosocial aspects of familial cancer, aiming to improve prevention, diagnosis, and treatment strategies. The journal serves as a valuable resource for researchers, clinicians, and genetic counselors involved in the field of hereditary cancer.
Details
Details
Abbr.
Fam Cancer
Publisher
Springer
Start
2000
End
Continuing
Frequency
Quarterly
p-ISSN
1389-9600
e-ISSN
1573-7292
Country
Netherlands
Language
English
Specialty
Oncology
Metrics
Metrics
h-index / Ranks: 5406
67
SJR / Ranks: 3717
1016
CiteScore / Ranks: 4922
5.10
JIF / Ranks: 4835
2.2
Recent Articles
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2.
Varde A, McVeigh T, Cuthill V, Brady A, DeSouza B, Latchford A, et al.
Fam Cancer
. 2025 Mar;
24(1):26.
PMID: 40045045
There is frequent uncertainty in both the precise quantification of risk, and the application of clinical interventions, designed to mitigate increased heritable colorectal cancer (CRC) susceptibility. We evaluated the role...
3.
Ong S, Chua Z, Yuen J, Chiang J, Zewen Z, Ngeow J, et al.
Fam Cancer
. 2025 Feb;
24(1):25.
PMID: 40011264
Cascade testing is often recommended for cancer predisposition syndromes, like Lynch syndrome (LS), to identify at-risk family members. The uptake of cascade testing is typically meditated by the proband's willingness...
4.
Merce F, Asla Q, Illana F, Victoria F, Javier H, Marta S, et al.
Fam Cancer
. 2025 Feb;
24(1):24.
PMID: 40009226
Multiple endocrine neoplasia type 4 (MEN4) is caused by a germline CDKN1B deleterious variant. CDKN1B encodes p27Kip1, a cyclin-dependent kinase inhibitor that acts as tumor-suppressor. Clinical presentation of MEN4 is...
5.
Weis L, Bychkovsky B, Hernandez A, Barroso-Sousa R, Sandoval R
Fam Cancer
. 2025 Feb;
24(1):23.
PMID: 39966186
Purpose: Management of cancer risks associated with the CHEK2 gene, a moderate penetrance breast cancer gene, is challenging in real-world practice. Family history, traditional breast cancer risk factors, and specific...
6.
Amiot J, Gubeljak L, Fontaine A, Smith D, Mortemousque I, Parodi N, et al.
Fam Cancer
. 2025 Feb;
24(1):22.
PMID: 39920491
Germline pathogenic variants of the RPS20 (ribosomal protein S20) gene are suspected to be involved in the predisposition to familial colorectal cancer (CRC) with no DNA mismatch repair deficiency. RPS20...
7.
Boedec M, Aucouturier C, Cavaille M, Leman R, Castera L, Delhomelle H, et al.
Fam Cancer
. 2025 Feb;
24(1):21.
PMID: 39920402
PTEN Hamartoma Tumor Syndrome (PHTS) is an autosomal dominant disorder characterized by high penetrance and significant phenotypic variability. In most patients, targeted high-throughput sequencing (HTS) approaches enable the detection of...
8.
Bove V, Spangenberg M, Ottati C, Vazquez L, Catalan A, Grille S
Fam Cancer
. 2025 Jan;
24(1):20.
PMID: 39890690
Germline variants in RUNX1 and DDX41 are well-established contributors to hereditary myeloid neoplasms and are increasingly recognized as critical predisposing factors in the developing myelodysplastic syndromes (MDS) and acute myeloid...
9.
de Langavant B, Lefevre J, Metras J, Dardenne A, OConnell L, Collard M, et al.
Fam Cancer
. 2025 Jan;
24(1):19.
PMID: 39890667
Familial adenomatous polyposis is an inherited genetic disorder responsible for multiple anomalies. Lifelong surveillance protocols are essential to detect and prevent adverse developments. However, limited data exist regarding the long-term...
10.
Abe N, Yamazaki F, Tsujikawa H, Kasuga R, Taniki N, Shimada H
Fam Cancer
. 2025 Jan;
24(1):18.
PMID: 39856486
Perivascular epithelioid cell tumors (PEComas) belong to a family of rare mesenchymal tumors composed of histologically and immunohistochemically distinctive perivascular epithelioid cells. Li-Fraumeni syndrome (LFS), an autosomal dominant cancer predisposition...