Luis Tecedor
Overview
Explore the profile of Luis Tecedor including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
19
Citations
682
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Jackson R, Keiser M, Meltzer J, Fykstra D, Dierksmeier S, Hajizadeh S, et al.
Mol Ther
. 2024 Mar;
32(5):1373-1386.
PMID: 38504517
Epidemiological studies show that individuals who carry the relatively uncommon APOE ε2 allele rarely develop Alzheimer disease, and if they do, they have a later age of onset, milder clinical...
2.
Jackson R, Keiser M, Meltzer J, Fykstra D, Dierksmeier S, Melloni A, et al.
bioRxiv
. 2023 Aug;
PMID: 37645718
One Sentence Summary: Introduction of ApoE2 using an AAV that transduces the ependymal cells of the ventricle causes a reduction in amyloid load and plaque associated synapse loss, and reduces...
3.
Carrell E, Chen Y, Ranum P, Coffin S, Singh L, Tecedor L, et al.
Mol Ther Nucleic Acids
. 2023 Aug;
33:296-304.
PMID: 37547292
Recombinant adeno-associated viral vectors (rAAVs) are a promising strategy to treat neurodegenerative diseases because of their ability to infect non-dividing cells and confer long-term transgene expression. Despite an ever-growing library...
4.
Ranum P, Tecedor L, Keiser M, Chen Y, Leib D, Liu X, et al.
Mol Ther
. 2023 Jan;
31(3):609-612.
PMID: 36610400
No abstract available.
5.
Ahrens-Nicklas R, Tecedor L, Hall A, Kane O, Chung R, Lysenko E, et al.
Mol Ther
. 2022 Apr;
30(7):2464-2473.
PMID: 35395398
Although neurologic symptoms occur in two-thirds of lysosomal storage disorders (LSDs), for most we do not understand the mechanisms underlying brain dysfunction. A major unanswered question is if the pathogenic...
6.
Monteys A, Hundley A, Ranum P, Tecedor L, Muehlmatt A, Lim E, et al.
Nature
. 2022 Feb;
602(7897):E25.
PMID: 35105975
No abstract available.
7.
Monteys A, Hundley A, Ranum P, Tecedor L, Muehlmatt A, Lim E, et al.
Nature
. 2021 Jul;
596(7871):291-295.
PMID: 34321659
So far, gene therapies have relied on complex constructs that cannot be finely controlled. Here we report a universal switch element that enables precise control of gene replacement or gene...
8.
Ahrens-Nicklas R, Tecedor L, Hall A, Lysenko E, Cohen A, Davidson B, et al.
JCI Insight
. 2019 Oct;
4(21).
PMID: 31573978
Accumulation of lysosomal storage material and late-stage neurodegeneration are hallmarks of lysosomal storage disorders (LSDs) affecting the brain. Yet, for most LSDs, including CLN3 disease, the most common form of...
9.
Beauvais G, Watson J, Aguirre J, Tecedor L, Ehrlich M, Gonzalez-Alegre P
Brain Res
. 2018 Oct;
1706:24-31.
PMID: 30366018
DYT1 dystonia is a neurological disease caused by a dominant mutation that results in the loss of a glutamic acid in the endoplasmic reticulum-resident protein torsinA. Currently, treatments are symptomatic...
10.
Schultz M, Tecedor L, Lysenko E, Ramachandran S, Stein C, Davidson B
Neurobiol Dis
. 2018 Apr;
115:182-193.
PMID: 29660499
The neuronal ceroid lipofuscinoses are a class of inherited neurodegenerative diseases characterized by the accumulation of autofluorescent storage material. The most common neuronal ceroid lipofuscinosis has juvenile onset with rapid...