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Ludger Klein-Hitpass

Explore the profile of Ludger Klein-Hitpass including associated specialties, affiliations and a list of published articles. Areas
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Articles 123
Citations 3710
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Recent Articles
11.
Johansson P, Klein-Hitpass L, Budeus B, Kuhn M, Lauber C, Seifert M, et al.
Cancers (Basel) . 2020 Apr; 12(4). PMID: 32316399
The pathogenesis of ocular adnexal marginal zone lymphomas of mucosa-associated lymphatic tissue-type (OAML) is not fully understood. We performed whole genome sequencing (WGS) and/or whole exome sequencing (WES) for 13...
12.
Kehrmann J, Effenberg L, Wilk C, Schoemer D, Phuong N, Adamczyk A, et al.
Immunology . 2019 Nov; 159(3):344-353. PMID: 31755554
A reciprocal interaction exists between the gut microbiota and the immune system. Regulatory T (Treg) cells are important for controlling immune responses and for maintaining the intestinal homeostasis but their...
13.
Junger S, Mynarek M, Wohlers I, Dorner E, Zur Muhlen A, Velez-Char N, et al.
Acta Neuropathol Commun . 2019 Nov; 7(1):181. PMID: 31727173
Introduction: Risk stratification of children with ependymomas of the posterior fossa in current therapeutic protocols is mainly based on clinical criteria. We aimed to identify independent outcome predictors for this...
14.
Kalmbach A, Schroder C, Klein-Hitpass L, Nordstrom K, Ulz P, Heitzer E, et al.
Cytogenet Genome Res . 2019 Oct; 159(1):1-11. PMID: 31658463
The switch/sucrose non-fermenting (SWI/SNF) complex is an ATP-dependent chromatin remodeller that regulates the spacing of nucleosomes and thereby controls gene expression. Heterozygous mutations in genes encoding subunits of the SWI/SNF...
15.
Mangolini M, Gotte F, Moore A, Ammon T, Oelsner M, Lutzny-Geier G, et al.
Nat Commun . 2018 Sep; 9(1):3839. PMID: 30242258
The Wnt signalling pathway, one of the core de-regulated pathways in chronic lymphocytic leukaemia (CLL), is activated in only a subset of patients through somatic mutations. Here we describe alternative,...
16.
Kehrmann J, Menzel J, Saeedghalati M, Obeid R, Schulze C, Holzendorf V, et al.
J Infect Dis . 2018 Sep; 219(3):497-508. PMID: 30202890
Background: Human immunodeficiency virus (HIV) infection is an independent risk factor for coronary heart disease (CHD) and is associated with perturbation of the gut microbiota. Methods: We analyzed gut microbiota...
17.
Prager P, Kunz M, Ebert R, Klein-Hitpass L, Sieker J, Barthel T, et al.
Knee Surg Relat Res . 2018 Mar; 30(3):193-205. PMID: 29554721
Purpose: Mesenchymal stem cells (MSCs) isolated from the anterior cruciate ligament (ACL) share multiple characteristics of bone marrow-derived mesenchymal stem cells (BMSCs), allowing their use for regenerative therapies. Injuries to...
18.
Leitao E, Beygo J, Zeschnigk M, Klein-Hitpass L, Bargull M, Rahmann S, et al.
Methods Mol Biol . 2018 Mar; 1767:351-366. PMID: 29524145
DNA methylation, i.e., the methylation of cytosine at carbon atom C5, has an important role in the regulation of gene expression. The methylation status of each cytosine in a specific...
19.
Johansson P, Klein-Hitpass L, Choidas A, Habenberger P, Mahboubi B, Kim B, et al.
Blood Cancer J . 2018 Jan; 8(1):11. PMID: 29352181
T-cell prolymphocytic leukemia (T-PLL) is an aggressive malignancy with a median survival of the patients of less than two years. Besides characteristic chromosomal translocations, frequent mutations affect the ATM gene,...
20.
Tucci F, Kitanovski S, Johansson P, Klein-Hitpass L, Kahraman A, Durig J, et al.
Blood . 2017 Dec; 131(5):546-557. PMID: 29242186
Patients chronically infected with hepatitis C virus (HCV) frequently develop mixed cryoglobulinemia (MC), a monoclonal expansion of immunoglobulin M (IgM) autoreactive B cells, and also have an increased B-cell lymphoma...