Tarik Moroy
Overview
Explore the profile of Tarik Moroy including associated specialties, affiliations and a list of published articles.
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106
Citations
3027
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Recent Articles
1.
Huang Q, H J Cao W, Curio S, Yu H, Denman R, Chen E, et al.
Sci Immunol
. 2024 May;
9(95):eadj2654.
PMID: 38820141
Tissue-resident innate lymphoid cells (ILCs) play a vital role in the frontline defense of various tissues, including the lung. The development of type 2 ILCs (ILC2s) depends on transcription factors...
2.
Subramani P, Fraszczak J, Helness A, Estall J, Moroy T, Di Noia J
EMBO Rep
. 2024 May;
25(6):2662-2697.
PMID: 38744970
The multifunctional RNA-binding protein hnRNPL is implicated in antibody class switching but its broader function in B cells is unknown. Here, we show that hnRNPL is essential for B cell...
3.
Frank D, Patnana P, Vorwerk J, Mao L, Gopal L, Jung N, et al.
Blood
. 2023 Sep;
142(25):2175-2191.
PMID: 37756525
Growth factor independence 1 (GFI1) is a DNA-binding transcription factor and a key regulator of hematopoiesis. GFI1-36N is a germ line variant, causing a change of serine (S) to asparagine...
4.
5.
Lacroix M, Beauchemin H, Khandanpour C, Moroy T
Front Oncol
. 2023 Apr;
13:1148936.
PMID: 37035206
DDX3X is an RNA helicase with many functions in RNA metabolism such as mRNA translation, alternative pre-mRNA splicing and mRNA stability, but also plays a role as a regulator of...
6.
Lacroix M, Beauchemin H, Moroy T
Expert Opin Ther Targets
. 2023 Jan;
26(12):1037-1040.
PMID: 36620925
No abstract available.
7.
Helness A, Fraszczak J, Joly-Beauparlant C, Bagci H, Trahan C, Arman K, et al.
Commun Biol
. 2022 Sep;
5(1):922.
PMID: 36071278
No abstract available.
8.
Winkler R, Magdefrau A, Piskor E, Kleemann M, Beyer M, Linke K, et al.
Oncogene
. 2022 Sep;
41(40):4560-4572.
PMID: 36068335
Overexpression of MYC is a genuine cancer driver in lymphomas and related to poor prognosis. However, therapeutic targeting of the transcription factor MYC remains challenging. Here, we show that inhibition...
9.
Lacroix M, Beauchemin H, Fraszczak J, Ross J, Shooshtarizadeh P, Chen R, et al.
Cancer Res
. 2022 Jul;
82(17):3172-3186.
PMID: 35815807
Significance: The sex-dependent effects of DDX3X deficiency in malignant transformation of B cells and the compensatory role of DDX3Y support inhibition of DDX3 as a treatment strategy for MYC-driven B-cell...
10.
Piskor E, Ross J, Moroy T, Kosan C
Biology (Basel)
. 2022 Apr;
11(4).
PMID: 35453704
Aging of the immune system is described as a progressive loss of the ability to respond to immunologic stimuli and is commonly referred to as immunosenescence. B cell immunosenescence is...