Lucio G Costa
Overview
Explore the profile of Lucio G Costa including associated specialties, affiliations and a list of published articles.
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Articles
139
Citations
3909
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Recent Articles
1.
Kodavanti P, Costa L, Aschner M
Adv Neurotoxicol
. 2023 Nov;
10:1-25.
PMID: 37920427
During the past century, a vast number of organic chemicals have been manufactured and used in industrial, agricultural, public health, consumer products, and other applications. The widespread use in bulk...
2.
Roque P, Barria A, Zhang X, Hashimoto J, Costa L, Guizzetti M
Neurochem Res
. 2023 Jul;
48(10):3212-3227.
PMID: 37402036
Astrocytes release numerous factors known to contribute to the process of synaptogenesis, yet knowledge about the signals that control their release is limited. We hypothesized that neuron-derived signals stimulate astrocytes,...
3.
Roque P, Barria A, Zhang X, Costa L, Guizzetti M
Res Sq
. 2023 Feb;
PMID: 36824819
Astrocytes release numerous factors known to contribute to the process of synaptogenesis, yet knowledge about the signals that control their release is limited. We hypothesized that neuron-derived signals stimulate astrocytes,...
4.
Garrick J, Cole T, Dao K, Phillips A, Costa L
Environ Toxicol
. 2023 Jan;
38(4):899-913.
PMID: 36629036
Epidemiological studies support an association between air pollution exposure, specifically particulate matter (PM), and neurodegenerative disease. Diesel exhaust (DE) is a principal component of ambient air pollution and a major...
5.
Garrick J, Dao K, Costa L, Marsillach J, Furlong C
BMC Neurosci
. 2022 Sep;
23(1):52.
PMID: 36056313
Background: Paraoxonase 2 (PON2) is an intracellular antioxidant enzyme located at the inner mitochondrial membrane. Previous studies have found PON2 to be an important antioxidant in a variety of cellular...
6.
Garrick J, Costa L, Cole T, Marsillach J
Curr Protoc
. 2021 Aug;
1(8):e220.
PMID: 34370398
Motor deficits can significantly affect the completion of daily life activities and have a negative impact on quality of life. Consequently, motor function is an important behavioral endpoint to measure...
7.
Garrick J, Cole T, Bammler T, MacDonald J, Marsillach J, Furlong C, et al.
Neurotoxicol Teratol
. 2021 Jul;
87:107010.
PMID: 34216730
Paraoxonase 2 (PON2) is an intracellular antioxidant enzyme shown to play an important role in mitigating oxidative stress in the brain. Oxidative stress is a common mechanism of toxicity for...
8.
Marsillach J, Richter R, Costa L, Furlong C
Curr Protoc
. 2021 Jan;
1(1):e25.
PMID: 33484495
Human paraoxonase-1 (PON1) is a high-density lipoprotein-associated enzyme with antioxidant, anti-inflammatory, and antiapoptotic roles. The ability of PON1 to hydrolyze specific organophosphate (OP) compounds and prevent accumulation of oxidized lipids...
9.
Cole T, Chang Y, Dao K, Daza R, Hevner R, Costa L
J Neurodev Disord
. 2020 Dec;
12(1):41.
PMID: 33327933
Background: Exposure to traffic-related air pollution (TRAP) during development and/or in adulthood has been associated in many human studies with both neurodevelopmental and neurodegenerative diseases, such as autism spectrum disorder...
10.
Poti F, Pozzoli C, Adami M, Poli E, Costa L
Acta Biomed
. 2020 May;
91(2):118-136.
PMID: 32420936
The Coronavirus disease 19 (COVID-19) outbreak has been recognized as a global threat to public health. It is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and no...