Lucia Sivilotti
Overview
Explore the profile of Lucia Sivilotti including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
131
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Recent Articles
1.
Mashanov G, Nenasheva T, Mashanova A, Lape R, Birdsall N, Sivilotti L, et al.
Faraday Discuss
. 2021 Oct;
232(0):358-374.
PMID: 34647559
Heterogeneity in cell membrane structure, typified by microdomains with different biophysical and biochemical properties, is thought to impact on a variety of cell functions. Integral membrane proteins act as nanometre-sized...
2.
Yu J, Zhu H, Lape R, Greiner T, Du J, Lu W, et al.
Cell
. 2021 Feb;
184(4):957-968.e21.
PMID: 33567265
Ligand-gated ion channels mediate signal transduction at chemical synapses and transition between resting, open, and desensitized states in response to neurotransmitter binding. Neurotransmitters that produce maximum open channel probabilities (Po)...
3.
Sivilotti L, Colquhoun D
J Gen Physiol
. 2016 Jul;
148(2):79-88.
PMID: 27432998
No abstract available.
4.
Medelin M, Rancic V, Cellot G, Laishram J, Veeraraghavan P, Rossi C, et al.
J Physiol
. 2016 Apr;
594(13):3827-40.
PMID: 27098371
Key Points: Increased environmental risk factors in conjunction with genetic susceptibility have been proposed with respect to the remarkable variations in mortality in amyotrophic lateral sclerosis (ALS). In vitro models...
5.
Marabelli A, Lape R, Sivilotti L
J Gen Physiol
. 2014 Dec;
145(1):23-45.
PMID: 25548135
Prokaryotic channels, such as Erwinia chrysanthemi ligand-gated ion channel (ELIC) and Gloeobacter violaceus ligand-gated ion channel, give key structural information for the pentameric ligand-gated ion channel family, which includes nicotinic...
6.
Yu R, Hurdiss E, Greiner T, Lape R, Sivilotti L, Biggin P
Biochemistry
. 2014 Sep;
53(38):6041-51.
PMID: 25184435
The human glycine receptor (hGlyR) is an anion-permeable ligand-gated channel that is part of a larger superfamily of receptors called the Cys-loop family. hGlyRs are particularly amenable to single-channel recordings,...
7.
Calderhead B, Epstein M, Sivilotti L, Girolami M
Methods Mol Biol
. 2013 May;
1021:247-72.
PMID: 23715989
We consider the Bayesian analysis of mechanistic models describing the dynamic behavior of ligand-gated ion channels. The opening of the transmembrane pore in an ion channel is brought about by...