» Articles » PMID: 27432998

In Praise of Single Channel Kinetics

Overview
Journal J Gen Physiol
Specialty Physiology
Date 2016 Jul 20
PMID 27432998
Citations 11
Authors
Affiliations
Soon will be listed here.
Citing Articles

Different Time Courses of Mono- and Bi-Liganded Bursts of Channel Openings of Adult nAChR Molecules Formed by the Reactions of Transmembrane Regions.

Ljaschenko D, Pauli M, Mrestani A, Dudel J, Heckmann M Cells. 2025; 13(24.

PMID: 39768170 PMC: 11674366. DOI: 10.3390/cells13242079.


Machine Learning Methods for the Analysis of the Patch-Clamp Signals.

Richter-Laskowska M, Wawrzkiewicz-Jalowiecka A, Bies A, Trybek P Methods Mol Biol. 2024; 2796:249-270.

PMID: 38856906 DOI: 10.1007/978-1-0716-3818-7_15.


Model-free idealization: Adaptive integrated approach for idealization of ion-channel currents.

Sato M, Hariyama M, Komiya M, Suzuki K, Tozawa Y, Yamamoto H Biophys J. 2023; 122(19):3959-3975.

PMID: 37634080 PMC: 10560676. DOI: 10.1016/j.bpj.2023.08.019.


Derepression may masquerade as activation in ligand-gated ion channels.

Tessier C, Emlaw J, Sturgeon R, daCosta C Nat Commun. 2023; 14(1):1907.

PMID: 37019877 PMC: 10076327. DOI: 10.1038/s41467-023-36770-z.


Analysis of patchclamp recordings: model-free multiscale methods and software.

Pein F, Eltzner B, Munk A Eur Biophys J. 2021; 50(2):187-209.

PMID: 33837454 PMC: 8071803. DOI: 10.1007/s00249-021-01506-8.


References
1.
Mukhtasimova N, Lee W, Wang H, Sine S . Detection and trapping of intermediate states priming nicotinic receptor channel opening. Nature. 2009; 459(7245):451-4. PMC: 2712348. DOI: 10.1038/nature07923. View

2.
Parzefall F, Wilhelm R, Heckmann M, Dudel J . Single channel currents at six microsecond resolution elicited by acetylcholine in mouse myoballs. J Physiol. 1998; 512 ( Pt 1):181-8. PMC: 2231182. DOI: 10.1111/j.1469-7793.1998.181bf.x. View

3.
Colquhoun D, Hatton C, Hawkes A . The quality of maximum likelihood estimates of ion channel rate constants. J Physiol. 2003; 547(Pt 3):699-728. PMC: 2342730. DOI: 10.1113/jphysiol.2002.034165. View

4.
Epstein M, Calderhead B, Girolami M, Sivilotti L . Bayesian Statistical Inference in Ion-Channel Models with Exact Missed Event Correction. Biophys J. 2016; 111(2):333-348. PMC: 4968427. DOI: 10.1016/j.bpj.2016.04.053. View

5.
Ohno K, Wang H, Milone M, Bren N, Brengman J, Nakano S . Congenital myasthenic syndrome caused by decreased agonist binding affinity due to a mutation in the acetylcholine receptor epsilon subunit. Neuron. 1996; 17(1):157-70. DOI: 10.1016/s0896-6273(00)80289-5. View