Lucia Chiummiento
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Explore the profile of Lucia Chiummiento including associated specialties, affiliations and a list of published articles.
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Articles
25
Citations
123
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Recent Articles
1.
Gentile D, Chiummiento L, Santarsiere A, Funicello M, Lupattelli P, Rescifina A, et al.
Viruses
. 2024 Mar;
16(3).
PMID: 38543704
The continuous emergence of SARS-CoV-2 variants caused the persistence of the COVID-19 epidemic and challenged the effectiveness of the existing vaccines. The viral proteases are the most attractive targets for...
2.
Caddeo C, Miglionico R, Rinaldi R, Nigro I, Lamorte D, Chiummiento L, et al.
Int J Mol Sci
. 2023 Mar;
24(5).
PMID: 36901980
Liver cancer is one of the most common causes of cancer death worldwide. In recent years, substantial progress has been made in the development of systemic therapies, but there is...
3.
Rinaldi R, Miglionico R, Nigro I, DOrsi R, Chiummiento L, Funicello M, et al.
Cells
. 2021 Nov;
10(11).
PMID: 34831275
Several pre-clinical and clinical reports suggest that HIV-1 protease inhibitors, in addition to the antiretroviral properties, possess pleiotropic pharmacological effects including anticancer action. Therefore, we investigated the pro-apoptotic activity in...
4.
Marsico M, Santarsiero A, Pappalardo I, Convertini P, Chiummiento L, Sardone A, et al.
Biomedicines
. 2021 Nov;
9(11).
PMID: 34829892
Metabolic reprogramming is a hallmark of cancer cells required to ensure high energy needs and the maintenance of redox balance. A relevant metabolic change of cancer cell bioenergetics is the...
5.
DOrsi R, Funicello M, Laurita T, Lupattelli P, Berti F, Chiummiento L
Biomolecules
. 2021 Nov;
11(11).
PMID: 34827582
Here, we report the synthesis, enzyme inhibition and structure-activity relationship studies of a new potent class of HIV-1 protease inhibitors, which contain a pseudo-symmetric hydroxyethylamine core and heteroarylcarboxyamide moieties. The...
6.
Masse P, Choppin S, Chiummiento L, Colobert F, Hanquet G
J Org Chem
. 2021 Jan;
86(3):3033-3040.
PMID: 33475349
We describe herein the first access to 12-membered cyclic[7,0],-diarylheptanoids. The key features of the synthesis include both a Suzuki-Miyaura coupling and a ring closing metathesis. Actinidione, a promising natural product,...
7.
Santarsiero A, Bochicchio A, Funicello M, Lupattelli P, Choppin S, Colobert F, et al.
Biochem Biophys Res Commun
. 2020 Aug;
529(4):1117-1123.
PMID: 32819574
In neurodegenerative diseases, such as Alzheimer's disease, Huntington's disease, Parkinson's disease and multiple sclerosis, neuroinflammation induced by the microglial activation plays a crucial role. In effort to develop effective anti-neuroinflammatory...
8.
Labanca F, Faraone I, Nole M, Hornedo-Ortega R, Russo D, Garcia-Parrilla M, et al.
Antioxidants (Basel)
. 2020 Aug;
9(8).
PMID: 32759838
The leaves of L. have been used for a long time in traditional medicine for the treatment of many ailments. Grape polyphenols, indeed, have been demonstrated to be able to...
9.
Chiummiento L, DOrsi R, Funicello M, Lupattelli P
Molecules
. 2020 May;
25(10).
PMID: 32429435
This review describes the progress of the last decade on the synthesis of substituted benzofurans, which are useful scaffolds for the synthesis of numerous natural products and pharmaceuticals. In particular,...
10.
Faraone I, Russo D, Chiummiento L, Fernandez E, Choudhary A, Monne M, et al.
Foods
. 2020 Feb;
9(2).
PMID: 32024045
The genus belonging to the Lamiaceae family, and is an important South American mint genus used commonly in folk medicine as an aroma in cooking. The phytochemical-rich samples of the...