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Lucas Lange

Explore the profile of Lucas Lange including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 91
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Recent Articles
1.
Dardano M, Kleemiss F, Kosanke M, Lang D, Wilson L, Franke A, et al.
Nat Cell Biol . 2024 Oct; 26(11):1984-1996. PMID: 39379702
Despite the biomedical importance of haematopoietic stem cells and haematopoietic progenitor cells, their in vitro stabilization in a developmental context has not been achieved due to limited knowledge of signals...
2.
Bolesani E, Bornhorst D, Iyer L, Zawada D, Friese N, Morgan M, et al.
Cardiovasc Res . 2024 Jun; 120(11):1295-1311. PMID: 38836637
Aims: Understanding the molecular identity of human pluripotent stem cell (hPSC)-derived cardiac progenitors and mechanisms controlling their proliferation and differentiation is valuable for developmental biology and regenerative medicine. Methods And...
3.
Lange L, Wenzlitschke N, Rahm E
Sensors (Basel) . 2024 May; 24(10). PMID: 38793906
Smartwatch health sensor data are increasingly utilized in smart health applications and patient monitoring, including stress detection. However, such medical data often comprise sensitive personal information and are resource-intensive to...
4.
Lange L, Esteban M, Schambach A
Signal Transduct Target Ther . 2022 Jul; 7(1):244. PMID: 35853857
No abstract available.
5.
Morgan M, Lange L, Schambach A
Signal Transduct Target Ther . 2022 Jul; 7(1):213. PMID: 35794105
No abstract available.
6.
Baron Y, Sens J, Lange L, Nassauer L, Klatt D, Hoffmann D, et al.
Mol Ther Nucleic Acids . 2022 Feb; 27:810-823. PMID: 35141043
DNA-modifying technologies, such as the CRISPR-Cas9 system, are promising tools in the field of gene and cell therapies. However, high and prolonged expression of DNA-modifying enzymes may cause cytotoxic and...
7.
Morgan M, Lange L, Schambach A
Signal Transduct Target Ther . 2021 Jul; 6(1):282. PMID: 34305139
No abstract available.
8.
Lange L, Morgan M, Schambach A
Cell Mol Life Sci . 2021 Feb; 78(9):4143-4160. PMID: 33559689
In vitro generation of hematopoietic cells and especially hematopoietic stem cells (HSCs) from human pluripotent stem cells (PSCs) are subject to intensive research in recent decades, as these cells hold...
9.
Sens J, Hoffmann D, Lange L, Vollmer Barbosa P, Morgan M, Falk C, et al.
Hum Gene Ther . 2020 Oct; 32(1-2):77-95. PMID: 33023317
Samples from patients with rare diseases, such as primary immunodeficiencies, are often limited, which hampers careful analysis of the pathomechanisms involved in immune cell dysregulation. To overcome this issue, induced...
10.
Lange L, Hoffmann D, Schwarzer A, Ha T, Philipp F, Lenz D, et al.
Stem Cell Reports . 2020 Jul; 15(1):274. PMID: 32668220
No abstract available.