Loukia Tsaprouni
Overview
Explore the profile of Loukia Tsaprouni including associated specialties, affiliations and a list of published articles.
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16
Citations
1428
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Recent Articles
1.
Jahangiri L, Pucci P, Ishola T, Trigg R, Williams J, Pereira J, et al.
Int J Mol Sci
. 2021 Aug;
22(16).
PMID: 34445233
MYC is a target of the Wnt signalling pathway and governs numerous cellular and developmental programmes hijacked in cancers. The amplification of MYC is a frequently occurring genetic alteration in...
2.
Jahangiri L, Ishola T, Pucci P, Trigg R, Pereira J, Williams J, et al.
Cancers (Basel)
. 2021 Apr;
13(6).
PMID: 33799834
Cancer stem cells (CSCs) possess properties such as self-renewal, resistance to apoptotic cues, quiescence, and DNA-damage repair capacity. Moreover, CSCs strongly influence the tumour microenvironment (TME) and may account for...
3.
Jahangiri L, Tsaprouni L, Trigg R, Williams J, Gkoutos G, Turner S, et al.
Open Biol
. 2020 Jul;
10(7):200121.
PMID: 32634370
Gene expression programmes driving cell identity are established by tightly regulated transcription factors that auto- and cross-regulate in a feed-forward manner, forming core regulatory circuitries (CRCs). CRC transcription factors create...
4.
Ju M, Short A, Thompson P, Bakerly N, Gkoutos G, Tsaprouni L, et al.
JAMIA Open
. 2020 Jan;
2(2):261-271.
PMID: 31984360
Objectives: Chronic obstructive pulmonary disease (COPD) phenotypes cover a range of lung abnormalities. To allow text mining methods to identify pertinent and potentially complex information about these phenotypes from textual...
5.
Zhang Y, Poobalasingam T, Yates L, Walker S, Taylor M, Chessum L, et al.
Dis Model Mech
. 2018 Jan;
11(1).
PMID: 29361513
We previously identified dipeptidylpeptidase 10 () on chromosome 2 as a human asthma susceptibility gene, through positional cloning. Initial association results were confirmed in many subsequent association studies but the...
6.
Wang Q, Abdul S, Almeida L, Ananiadou S, Balderas-Martinez Y, Batista-Navarro R, et al.
Database (Oxford)
. 2016 Sep;
2016.
PMID: 27589961
Fully automated text mining (TM) systems promote efficient literature searching, retrieval, and review but are not sufficient to produce ready-to-consume curated documents. These systems are not meant to replace biocurators,...
7.
Gkoutos G, Hoehndorf R, Tsaprouni L, Schofield P
Mamm Genome
. 2015 Jul;
26(9-10):540-7.
PMID: 26215546
The development of ontologies for describing animal behaviour has proved to be one of the most difficult of all scientific knowledge domains. Ranging from neurological processes to human emotions, the...
8.
Dick K, Nelson C, Tsaprouni L, Sandling J, Aissi D, Wahl S, et al.
Lancet
. 2014 Mar;
383(9933):1990-8.
PMID: 24630777
Background: Obesity is a major health problem that is determined by interactions between lifestyle and environmental and genetic factors. Although associations between several genetic variants and body-mass index (BMI) have...
9.
Menni C, Kastenmuller G, Petersen A, Bell J, Psatha M, Tsai P, et al.
Int J Epidemiol
. 2013 Jul;
42(4):1111-9.
PMID: 23838602
Background: Human ageing is a complex, multifactorial process and early developmental factors affect health outcomes in old age. Methods: Metabolomic profiling on fasting blood was carried out in 6055 individuals...
10.
Grundberg E, Small K, Hedman A, Nica A, Buil A, Keildson S, et al.
Nat Genet
. 2012 Sep;
44(10):1084-9.
PMID: 22941192
Sequence-based variation in gene expression is a key driver of disease risk. Common variants regulating expression in cis have been mapped in many expression quantitative trait locus (eQTL) studies, typically...