Louis M Pelus
Overview
Explore the profile of Louis M Pelus including associated specialties, affiliations and a list of published articles.
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79
Citations
2366
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Recent Articles
1.
Langevin B, Singh P, Plett P, Sampson C, Masters A, Gibbs A, et al.
Radiat Res
. 2023 Nov;
201(1):7-18.
PMID: 38019093
Exposure to high-dose ionizing radiation can lead to life-threatening injuries and mortality. Bone marrow is the most sensitive organ to radiation damage, resulting in the hematopoietic acute radiation syndrome (H-ARS)...
2.
Wu T, Pelus L, Plett P, Sampson C, Chua H, Fisher A, et al.
Radiat Res
. 2023 Apr;
199(5):468-489.
PMID: 37014943
Survivors of acute radiation exposure suffer from the delayed effects of acute radiation exposure (DEARE), a chronic condition affecting multiple organs, including lung, kidney, heart, gastrointestinal tract, eyes, and brain,...
3.
Fukuda S, Matsuda N, Shoji T, Onishi C, Hirade T, Taketani T, et al.
Leuk Res
. 2022 Dec;
124:106983.
PMID: 36473282
CXCR4 antagonists sensitize FLT3/ITD AML cells to FLT3 inhibitors; however, CXCR4 signaling can induce apoptosis in AML cells, raising the question of whether CXCR4 signaling exerts divergent effects on FLT3/ITD...
4.
Plett P, Pelus L, Orschell C
Methods Mol Biol
. 2022 Oct;
2567:251-262.
PMID: 36255706
The hematopoietic system is one of the most sensitive tissues to ionizing radiation, and radiation doses from 2 to 10 gray can result in death from bleeding and infection if...
5.
Patterson A, Orschell C, Pelus L
Methods Mol Biol
. 2022 Oct;
2567:127-140.
PMID: 36255699
Radiation exposure is particularly damaging to cells of the hematopoietic system, inducing pancytopenia and bone marrow failure. The study of these processes, as well as the development of treatments to...
6.
Hoggatt J, Pelus L
Methods Mol Biol
. 2022 Oct;
2567:3-7.
PMID: 36255691
Hematopoietic stem cells (HSCs) support the lifelong production of hundreds of billions of blood cells per day. This unique, incredible ability of HSCs also creates an incredible therapeutic potential for...
7.
Patterson A, Vemula S, Plett P, Sampson C, Chua H, Fisher A, et al.
Radiat Res
. 2022 Jul;
198(3):221-242.
PMID: 35834823
The hematopoietic system is highly sensitive to stress from both aging and radiation exposure, and the hematopoietic acute radiation syndrome (H-ARS) should be modeled in the geriatric context separately from...
8.
Liu L, Li H, Patterson A, Plett P, Sampson C, Mohammad K, et al.
Stem Cell Rev Rep
. 2022 Mar;
18(4):1478-1494.
PMID: 35318613
Exposure to potentially lethal high-dose ionizing radiation results in bone marrow suppression, known as the hematopoietic acute radiation syndrome (H-ARS), which can lead to pancytopenia and possible death from hemorrhage...
9.
Patterson A, Zhang S, Liu L, Li H, Singh P, Liu Y, et al.
Stem Cell Rev Rep
. 2021 Sep;
17(6):2124-2138.
PMID: 34510361
Autologous stem cell transplantation (ASCT) is a potentially curative therapy but requires collection of sufficient blood stem cells (PBSC). Up to 40 % of patients with multiple myeloma (MM) fail...
10.
Singh P, Pelus L
Stem Cell Rev Rep
. 2021 Jun;
17(6):2338-2346.
PMID: 34159458
The factors/mechanisms regulating multipotent or bipotent hematopoietic progenitor cells lineage-commitment are not well understood. In this study, we found that prostaglandin E (PGE) is a crucial physiological regulator of lineage...