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Louis C Morrill

Explore the profile of Louis C Morrill including associated specialties, affiliations and a list of published articles. Areas
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Articles 52
Citations 429
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Recent Articles
1.
Maashi H, Husayni A, M K, Reid M, Harnedy J, Herneman E, et al.
Org Lett . 2024 Oct; 26(42):9051-9055. PMID: 39432540
Herein we report an electrochemical deconstructive functionalization approach for the synthesis of C(sp)-rich heterocycles. The reaction proceeds the mesolytic cleavage of anodically generated aromatic radical cations and the trapping of...
2.
Bari M, Elsherbeni S, Maqbool T, Latham D, Gushlow E, Harper E, et al.
J Org Chem . 2024 Sep; 89(19):14571-14576. PMID: 39320102
Herein, we report an iron-catalyzed transfer hydrogenation of allylic alcohols. The operationally simple protocol employs a well-defined bench stable (cyclopentadienone)iron(0) carbonyl complex as a precatalyst in combination with KCO (4...
3.
Maashi H, Lewis-Atwell T, Harnedy J, Grayson M, Morrill L
Chemistry . 2024 Sep; 30(65):e202403413. PMID: 39287365
Herein, we report a mechanistic investigation of a recently developed electrochemical method for the deconstructive methoxylation of arylalcohols. A combination of synthetic, electroanalytical, and computational experiments have been performed to...
4.
Maashi H, Husayni A, Harnedy J, Morrill L
Chem Commun (Camb) . 2024 Sep; 60(80):11190-11201. PMID: 39268719
This highlight summarises electrochemical approaches for the deconstructive functionalization of arylcycloalkanes the fragmentation of anodically generated aromatic radical cations. A diverse range of deconstructive functionalization processes is described, including discussion...
5.
Elsherbeni S, Melen R, Pulis A, Morrill L
J Org Chem . 2024 Feb; 89(6):4244-4248. PMID: 38389441
Herein, we report a synthetic method to access a range of highly substituted indoles via the B(CF)-catalyzed transfer of 2° alkyl groups from amines. The transition-metal-free catalytic approach has been...
6.
El Gehani A, Maashi H, Harnedy J, Morrill L
Chem Commun (Camb) . 2023 Mar; 59(25):3655-3664. PMID: 36877137
This highlight summarises electrochemical approaches for the generation and utilization of alkoxy radicals, predominantly focusing on recent advances (2012-present). The application of electrochemically generated alkoxy radicals in a diverse range...
7.
Harnedy J, Maashi H, El Gehani A, Burns M, Morrill L
Org Lett . 2023 Feb; 25(9):1486-1490. PMID: 36847269
Herein we report an electrochemical approach for the deconstructive functionalization of cycloalkanols, where various alcohols, carboxylic acids, and -heterocycles are employed as nucleophiles. The method has been demonstrated across a...
8.
Kustiana B, Melen R, Morrill L
Org Lett . 2022 Nov; 24(47):8694-8697. PMID: 36394303
Herein, we report a one-pot synthesis of styrene derivatives via a novel B(CF)-catalyzed -selective isomerization of readily accessible allyl silanes and subsequent Hiyama coupling of the versatile alkenyl silane intermediates....
9.
Jones A, Williams M, Morrill L, Browne D
ACS Catal . 2022 Nov; 12(21):13681-13689. PMID: 36366760
The cross-electrophile coupling of either twisted-amides or heteroaryl halides with alkyl halides, enabled by ball-milling, is herein described. The operationally simple nickel-catalyzed process has no requirement for inert atmosphere or...
10.
Kustiana B, Elsherbeni S, Linford-Wood T, Melen R, Grayson M, Morrill L
Chemistry . 2022 Aug; 28(63):e202202454. PMID: 35943082
Herein, we report the B(C F ) -catalyzed E-selective isomerization of alkenes. The transition-metal-free method is applicable across a diverse array of readily accessible substrates, giving access to a broad...