Lorenzo Uccellini
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Explore the profile of Lorenzo Uccellini including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
282
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0
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Recent Articles
1.
ODonnell M, Larsen M, Brown T, Jain P, Munsamy V, Wolf A, et al.
Antimicrob Agents Chemother
. 2019 May;
63(6).
PMID: 31126923
No abstract available.
2.
ODonnell M, Larsen M, Brown T, Jain P, Munsamy V, Wolf A, et al.
Antimicrob Agents Chemother
. 2019 Jan;
63(4).
PMID: 30670422
A critical gap in tuberculosis (TB) treatment is detection of emergent drug resistance. We hypothesized that advanced phenotyping with whole-genome sequencing (WGS) will detect low-frequency drug resistance. We assessed a...
3.
Tomei S, Bedognetti D, De Giorgi V, Sommariva M, Civini S, Reinboth J, et al.
Mol Oncol
. 2014 Sep;
9(1):93-104.
PMID: 25174651
Background: The existence of a dichotomy between immunologically active and quiescent tumor phenotypes has been recently recognized in several types of cancer. The activation of a Th1 type of immune...
4.
Uccellini L, Ossiboff R, de Matos R, Morrisey J, Petrosov A, Navarrete-Macias I, et al.
Virol J
. 2014 Aug;
11:144.
PMID: 25106433
Background: Respiratory infections are important causes of morbidity and mortality in reptiles; however, the causative agents are only infrequently identified. Findings: Pneumonia, tracheitis and esophagitis were reported in a collection...
5.
Liu Q, Tomei S, Ascierto M, De Giorgi V, Bedognetti D, Dai C, et al.
J Clin Invest
. 2014 Apr;
124(5):2147-59.
PMID: 24691438
In multiple forms of cancer, constitutive activation of type I IFN signaling is a critical consequence of immune surveillance against cancer; however, PBMCs isolated from cancer patients exhibit depressed STAT1...
6.
Wang E, Zhao Y, Monaco A, Uccellini L, Kirkwood J, Spyropoulou-Vlachou M, et al.
PLoS One
. 2012 Aug;
7(7):e40805.
PMID: 22911710
Purpose: IFNa was the first cytokine to demonstrate anti-tumor activity in advanced melanoma. Despite the ability of high-dose IFNa reducing relapse and mortality by up to 33%, large majority of...
7.
Uccellini L, De Giorgi V, Zhao Y, Tumaini B, Erdenebileg N, Dudley M, et al.
J Transl Med
. 2012 Aug;
10:170.
PMID: 22909381
Background: Interferon regulatory factor (IRF)-5 is a transcription factor involved in type I interferon signaling whose germ line variants have been associated with autoimmune pathogenesis. Since relationships have been observed...
8.
Wang E, Uccellini L, Marincola F
Oncoimmunology
. 2012 Jul;
1(4):520-525.
PMID: 22754772
A cancer immune signature implicating good prognosis and responsiveness to immunotherapy was described that is observed also in other aspects of immune-mediated, tissue-specific destruction (TSD). Its determinism remains, however, elusive....
9.
Tomei S, Adams S, Uccellini L, Bedognetti D, De Giorgi V, Erdenebileg N, et al.
Med Oncol
. 2012 May;
29(5):3456-61.
PMID: 22618666
HRAS belongs to the RAS genes superfamily. RAS genes are important players in several human tumors and the single-nucleotide polymorphism rs12628 has been shown to contribute to the risk of...
10.
Spivey T, De Giorgi V, Zhao Y, Bedognetti D, Pos Z, Liu Q, et al.
BMC Genomics
. 2012 Apr;
13:156.
PMID: 22537248
Background: The weight that gene copy number plays in transcription remains controversial; although in specific cases gene expression correlates with copy number, the relationship cannot be inferred at the global...