Lisa S Cunden
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Explore the profile of Lisa S Cunden including associated specialties, affiliations and a list of published articles.
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8
Citations
210
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Recent Articles
1.
Cunden L, Nolan E
Methods Mol Biol
. 2019 Feb;
1929:379-395.
PMID: 30710286
Human S100A7 (psoriasin) is a metal-chelating host-defense protein expressed by epithelial cells. S100A7 possesses two Cys residues that generate two redox isoforms of the protein. In the oxidized form (S100A7),...
2.
Cunden L, Nolan E
Biochemistry
. 2018 Jan;
57(11):1673-1680.
PMID: 29381858
The human innate immune system launches a metal-withholding response to starve invading microbial pathogens of essential metal nutrients. Zn(II)-sequestering proteins of the human S100 family contribute to this process and...
3.
Richardson C, Cunden L, Butty V, Nolan E, Lippard S, Shoulders M
J Am Chem Soc
. 2018 Jan;
140(7):2413-2416.
PMID: 29334734
We describe the preparation, evaluation, and application of an S100A12 protein-conjugated solid support, hereafter the "A12-resin", that can remove 99% of Zn(II) from complex biological solutions without significantly perturbing the...
4.
Cunden L, Brophy M, Rodriguez G, Flaxman H, Nolan E
Biochemistry
. 2017 Oct;
56(43):5726-5738.
PMID: 28976190
Human S100A7 (psoriasin) is a metal-chelating protein expressed by epithelial cells. It is a 22-kDa homodimer with two EF-hand domains per subunit and two transition-metal-binding HisAsp sites at the dimer...
5.
Nakashige T, Stephan J, Cunden L, Brophy M, Wommack A, Keegan B, et al.
J Am Chem Soc
. 2016 Aug;
138(37):12243-51.
PMID: 27541598
Human calprotectin (CP, S100A8/S100A9 oligomer, MRP-8/MRP-14 oligomer) is an abundant host-defense protein that is involved in the metal-withholding innate immune response. CP coordinates a variety of divalent first-row transition metal...
6.
Cunden L, Gaillard A, Nolan E
Chem Sci
. 2016 Feb;
7(2):1338-1348.
PMID: 26913170
Human S100A12 is a host-defense protein expressed and released by neutrophils that contributes to innate immunity. Apo S100A12 is a 21-kDa antiparallel homodimer that harbors two Ca(II)-binding EF-hand domains per...
7.
Hayden J, Brophy M, Cunden L, Nolan E
J Am Chem Soc
. 2013 Jan;
135(2):775-87.
PMID: 23276281
Calprotectin (CP) is a transition metal-chelating antimicrobial protein of the calcium-binding S100 family that is produced and released by neutrophils. It inhibits the growth of various pathogenic microorganisms by sequestering...
8.
Cunden L, Linck R
Inorg Chem
. 2011 Apr;
50(10):4428-36.
PMID: 21506587
The M(CO)(4) fragment can be assigned to be isolobal with both CH(3)(+) and CH(2). In order to investigate this ambiguous isolobal assignment, we report calculations on compounds of the type...