Lisa Pike
Overview
Explore the profile of Lisa Pike including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
398
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Recent Articles
1.
Yang Y, Lane A, Ricketts C, Sourbier C, Wei M, Shuch B, et al.
PLoS One
. 2013 Aug;
8(8):e72179.
PMID: 23967283
Fumarate hydratase (FH)-deficient kidney cancer undergoes metabolic remodeling, with changes in mitochondrial respiration, glucose, and glutamine metabolism. These changes represent multiple biochemical adaptations in glucose and fatty acid metabolism that...
2.
Yang Y, Valera V, Sourbier C, Vocke C, Wei M, Pike L, et al.
Cancer Genet
. 2012 Aug;
205(7-8):377-90.
PMID: 22867999
The role of energy deregulation and altered/adapted metabolism in tumor cells is an increasingly important issue in understanding cancer. Hereditary leiomyomatosis and renal cell carcinoma (HLRCC) is an aggressive form...
3.
Cvrljevic A, Akhavan D, Wu M, Martinello P, Furnari F, Johnston A, et al.
J Cell Sci
. 2011 Sep;
124(Pt 17):2938-50.
PMID: 21878501
A common mutation of the epidermal growth factor receptor in glioma is the de2-7EGFR (or EGFRvIII). Glioma cells expressing de2-7EGFR contain an intracellular pool of receptor with high levels of...
4.
Deliolanis N, Wurdinger T, Pike L, Tannous B, Breakefield X, Weissleder R, et al.
Biomed Opt Express
. 2011 Apr;
2(4):887-900.
PMID: 21483611
We have developed a spectral inversion method for three-dimensional tomography of far-red and near-infrared fluorescent proteins in animals. The method was developed in particular to address the steep light absorption...
5.
Niers J, Kerami M, Pike L, Lewandrowski G, Tannous B
Mol Ther
. 2011 Feb;
19(6):1090-6.
PMID: 21343914
Noninvasive detection and in vivo imaging of apoptosis plays a critical role in the development of therapeutics in many different fields including cancer. We have developed an apoptosis biosensor by...
6.
Maguire C, Deliolanis N, Pike L, Niers J, Tjon-Kon-Fat L, Sena-Esteves M, et al.
Anal Chem
. 2009 Jul;
81(16):7102-6.
PMID: 19601604
Gaussia luciferase (Gluc) is a sensitive reporter for studying different biological processes such as gene expression, promoter activity, protein-protein interactions, signal transduction, as well as tumor cell growth and response...
7.
Tannous B, Christensen A, Pike L, Wurdinger T, Perry K, Saydam O, et al.
Mol Ther
. 2009 Mar;
17(5):810-9.
PMID: 19259066
Viral vectors have been used to deliver a wide range of therapeutic genes to tumors. In this study, a novel tumor therapy was achieved by the delivery of a mammalian...
8.
Wurdinger T, Badr C, Pike L, de Kleine R, Weissleder R, Breakefield X, et al.
Nat Methods
. 2008 Jan;
5(2):171-3.
PMID: 18204457
Luciferases are widely used to monitor biological processes. Here we describe the naturally secreted Gaussia princeps luciferase (Gluc) as a highly sensitive reporter for quantitative assessment of cells in vivo...
9.
Pike L, Petravicz J, Wang S
J Gene Med
. 2006 Apr;
8(7):804-13.
PMID: 16602134
Background: Firefly luciferase (Fluc) has routinely been used to quantitate and analyze gene expression in vitro by measuring the photons emitted after the addition of ATP and luciferin to a...