Lisa Marie Munter
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Explore the profile of Lisa Marie Munter including associated specialties, affiliations and a list of published articles.
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12
Citations
81
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Recent Articles
1.
Eta-secretase-like processing of the amyloid precursor protein (APP) by the rhomboid protease RHBDL4
Penalva Y, Paschkowsky S, Recinto S, Duchesne A, Hammond T, Spiegler P, et al.
J Biol Chem
. 2024 Jul;
300(8):107541.
PMID: 38992438
The amyloid precursor protein (APP) is a key protein in Alzheimer's disease synthesized in the endoplasmic reticulum (ER) and translocated to the plasma membrane where it undergoes proteolytic cleavages by...
2.
Penalva Y, Paschkowsky S, Yang J, Recinto S, Cinkorpumin J, Hernandez M, et al.
bioRxiv
. 2024 Mar;
PMID: 38464180
Characteristic cerebral pathological changes of Alzheimer's disease (AD) such as glucose hypometabolism or the accumulation of cleavage products of the amyloid precursor protein (APP), known as Aβ peptides, lead to...
3.
Phenix J, Cote J, Dieme D, Recinto S, Oestereich F, Efrem S, et al.
Front Pharmacol
. 2023 Aug;
14:1171937.
PMID: 37533630
High levels of plasma cholesterol, especially high levels of low-density lipoprotein cholesterol (LDL-C), have been associated with an increased risk of Alzheimer's disease. The cholesteryl ester transfer protein (CETP) in...
4.
Hsiao J, Penalva Y, Yee-Li Wu H, Xiao B, Jansen G, Dejgaard K, et al.
Biochemistry
. 2023 Mar;
62(6):1209-1218.
PMID: 36857408
The physiological functions of the rhomboid-related protein 4 (RHBDL4) are emerging, but their molecular details remain unclear. Because increased expression of RHBDL4 has been clinically linked to poorer outcomes in...
5.
Oestereich F, Yousefpour N, Yang E, Phenix J, Nezhad Z, Nitu A, et al.
J Lipid Res
. 2022 Aug;
63(9):100260.
PMID: 35921880
The cholesteryl ester transfer protein (CETP) is a lipid transfer protein responsible for the exchange of cholesteryl esters and triglycerides between lipoproteins. Decreased CETP activity is associated with longevity, cardiovascular...
6.
Munter L
J Neurochem
. 2020 May;
154(1):7-10.
PMID: 32374412
It may not be surprising that the brain as a lipid-rich organ shows perturbed lipid profiles in neurodegenerative conditions such as Alzheimer's disease. It is, however, more challenging to detect...
7.
Recinto S, Paschkowsky S, Munter L
Biol Chem
. 2018 Sep;
399(12):1399-1408.
PMID: 30171808
Since the first genetic description of a rhomboid in Drosophila melanogaster, tremendous efforts have been geared towards elucidating the proteolytic mechanism of this particular class of intramembrane proteases. In particular,...
8.
Paschkowsky S, Recinto S, Young J, Bondar A, Munter L
J Biol Chem
. 2018 Aug;
293(40):15556-15568.
PMID: 30143535
In the last decade, intramembrane proteases have gained increasing attention because of their many links to various diseases. Nevertheless, our understanding as to how they function or how they are...
9.
Paschkowsky S, Hsiao J, Young J, Munter L
Biochem Cell Biol
. 2018 Aug;
97(3):265-269.
PMID: 30102867
Proteases carry out a wide variety of physiological functions. This review presents a brief history of protease research, starting with the original discovery of pepsin in 1836. Following the path...
10.
Paschkowsky S, Oestereich F, Munter L
J Membr Biol
. 2017 Dec;
251(3):369-378.
PMID: 29260282
Proteases, sharp yet unforgivable tools of every cell, require tight regulation to ensure specific non-aberrant cleavages. The relatively recent discovered class of intramembrane proteases has gained increasing interest due to...