Lisa M Lindqvist
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Explore the profile of Lisa M Lindqvist including associated specialties, affiliations and a list of published articles.
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23
Citations
3925
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Recent Articles
1.
Gamell C, Bankovacki A, Scalzo-Inguanti K, Sedgmen B, Alhamdoosh M, Gail E, et al.
Br J Dermatol
. 2023 Jan;
188(5):636-648.
PMID: 36691791
Background: Neutrophils have been shown to contribute to the pathophysiology of hidradenitis suppurativa (HS), a chronic, painful and debilitating inflammatory skin disease, yet their exact role remains to be fully...
2.
Dong L, Reljic B, Cheung J, Ng E, Lindqvist L, Elefanty A, et al.
Cell Death Differ
. 2019 Feb;
26(10):2074-2085.
PMID: 30770875
Withdrawal of the growth factor interleukin-3 (IL-3) from IL-3-dependent myeloid cells causes them to undergo Bax/Bak1-dependent apoptosis, whereas factor-deprived BaxBak1 cells remain viable, but arrest and shrink. It was reported...
3.
Frank D, Vaux D, Murphy J, Vince J, Lindqvist L
J Cell Sci
. 2019 Feb;
132(5).
PMID: 30709919
Necroptosis is an inflammatory form of programmed cell death mediated by the pseudokinase mixed-lineage kinase domain-like protein (MLKL). Upon phosphorylation by receptor-interacting protein kinase-3 (RIPK3), MLKL oligomerizes, and translocates to...
4.
Tailler M, Lindqvist L, Gibson L, Adams J
Cell Death Differ
. 2018 Dec;
26(9):1766-1781.
PMID: 30538285
Drugs targeting various pro-survival BCL-2 family members (''BH3 mimetics'') have efficacy in hemopoietic malignancies, but the non-targeted pro-survival family members can promote resistance. Pertinently, the sensitivity of some tumor cell...
5.
Vince J, De Nardo D, Gao W, Vince A, Hall C, McArthur K, et al.
Cell Rep
. 2018 Nov;
25(9):2339-2353.e4.
PMID: 30485804
Intrinsic apoptosis resulting from BAX/BAK-mediated mitochondrial membrane damage is regarded as immunologically silent. We show here that in macrophages, BAX/BAK activation results in inhibitor of apoptosis (IAP) protein degradation to...
6.
Janic A, Valente L, Wakefield M, Stefano L, Milla L, Wilcox S, et al.
Nat Med
. 2018 Jun;
24(7):947-953.
PMID: 29892060
It has long been assumed that p53 suppresses tumor development through induction of apoptosis, possibly with contributions by cell cycle arrest and cell senescence. However, combined deficiency in these three...
7.
Dite T, Langendorf C, Hoque A, Galic S, Rebello R, Ovens A, et al.
J Biol Chem
. 2018 Apr;
293(23):8874-8885.
PMID: 29695504
Inhibition of the metabolic regulator AMP-activated protein kinase (AMPK) is increasingly being investigated for its therapeutic potential in diseases where AMPK hyperactivity results in poor prognoses, as in established cancers...
8.
Lindqvist L, Frank D, McArthur K, Dite T, Lazarou M, Oakhill J, et al.
Cell Death Differ
. 2017 Dec;
25(4):784-796.
PMID: 29229994
Cells undergoing Bax/Bak-mediated apoptosis exhibit signs of autophagy, but how it is activated and its significance is unknown. By directly activating Bax/Bak with BH3-only proteins or BH3 mimetic compounds, we...
9.
Lindqvist L, Tandoc K, Topisirovic I, Furic L
Curr Opin Genet Dev
. 2017 Nov;
48:104-111.
PMID: 29179096
Translation is a pivotal step in the regulation of gene expression as well as one of the most energy consuming processes in the cell. Dysregulation of translation caused by the...
10.
Conos S, Lindqvist L, Vince J
Methods Mol Biol
. 2017 Nov;
1714:229-236.
PMID: 29177866
Cell death results in the breakdown of the plasma membrane, which can cause the release of cytosolic proteins. During caspase-1-mediated cell death, termed pyroptosis, pro-inflammatory mediators that lack canonical secretory...