Lisa Craig
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Explore the profile of Lisa Craig including associated specialties, affiliations and a list of published articles.
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41
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2210
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Recent Articles
11.
Craig L, Forest K, Maier B
Nat Rev Microbiol
. 2019 Apr;
17(7):429-440.
PMID: 30988511
The surfaces of many bacteria are decorated with long, exquisitely thin appendages called type IV pili (T4P), dynamic filaments that are rapidly polymerized and depolymerized from a pool of pilin...
12.
Kolappan S, Lo K, Shen C, Guttman J, Craig L
Acta Crystallogr D Struct Biol
. 2017 Oct;
73(Pt 10):814-821.
PMID: 28994410
Francisella tularensis is a potent human pathogen that invades and survives in macrophage and epithelial cells. Two identical proteins, FTT_0924 from F. tularensis subsp. tularensis and FTL_1286 from F. tularensis...
13.
Caverly Rae J, Craig L, Slone T, Frame S, Buxton L, Kennedy G
Toxicol Rep
. 2017 Oct;
2:939-949.
PMID: 28962433
Ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)-propanoate, developed for use as a polymerization processing aid in the manufacture of fluoropolymers, was tested for its potential chronic toxicity and carcinogenicity in a 2-year oral dosing study...
14.
Wang F, Coureuil M, Osinski T, Orlova A, Altindal T, Gesbert G, et al.
Structure
. 2017 Sep;
25(9):1423-1435.e4.
PMID: 28877506
We report here cryoelectron microscopy reconstructions of type IV pili (T4P) from two important human pathogens, Pseudomonas aeruginosa and Neisseria gonorrhoeae, at ∼ 8 and 5 Å resolution, respectively. The...
15.
Ng D, Harn T, Altindal T, Kolappan S, Marles J, Lala R, et al.
PLoS Pathog
. 2016 Dec;
12(12):e1006109.
PMID: 27992883
Type IV pilus (T4P) systems are complex molecular machines that polymerize major pilin proteins into thin filaments displayed on bacterial surfaces. Pilus functions require rapid extension and depolymerization of the...
16.
Kolappan S, Coureuil M, Yu X, Nassif X, Egelman E, Craig L
Nat Commun
. 2016 Oct;
7:13015.
PMID: 27698424
Neisseria meningitidis use Type IV pili (T4P) to adhere to endothelial cells and breach the blood brain barrier, causing cause fatal meningitis. T4P are multifunctional polymers of the major pilin...
17.
Kolappan S, Ng D, Yang G, Harn T, Craig L
J Biol Chem
. 2015 Sep;
290(43):25805-18.
PMID: 26324721
Type IV pili are extracellular polymers of the major pilin subunit. These subunits are held together in the pilus filament by hydrophobic interactions among their N-terminal α-helices, which also anchor...
18.
Kolappan S, Shen D, Mosi R, Sun J, McEachern E, Vocadlo D, et al.
Acta Crystallogr D Biol Crystallogr
. 2015 Feb;
71(Pt 2):185-95.
PMID: 25664730
Lactate dehydrogenase (LDH) is an essential metabolic enzyme that catalyzes the interconversion of pyruvate and lactate using NADH/NAD(+) as a co-substrate. Many cancer cells exhibit a glycolytic phenotype known as...
19.
Yuen A, Kolappan S, Ng D, Craig L
Mol Microbiol
. 2013 Oct;
90(4):898-918.
PMID: 24106767
Enterotoxigenic Escherichia coli (ETEC) colonize the human gut, causing severe cholera-like diarrhoea. ETEC utilize a diverse array of pili and fimbriae for host colonization, including the Type IVb pilus CFA/III....
20.
Melville S, Craig L
Microbiol Mol Biol Rev
. 2013 Sep;
77(3):323-41.
PMID: 24006467
Type IV pili (T4P) are surface-exposed fibers that mediate many functions in bacteria, including locomotion, adherence to host cells, DNA uptake (competence), and protein secretion and that can act as...