Lionel Blanchet
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Explore the profile of Lionel Blanchet including associated specialties, affiliations and a list of published articles.
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24
Citations
392
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Recent Articles
1.
Hintzen K, Blanchet L, Smolinska A, Boumans M, Stobberingh E, Dallinga J, et al.
PLoS One
. 2024 Jan;
19(1):e0297086.
PMID: 38277384
Introduction: Early and reliable determination of bacterial strain specificity and antibiotic resistance is critical to improve sepsis treatment. Previous research demonstrated the potential of headspace analysis of volatile organic compounds...
2.
Blanchet L, Vitale R, van Vorstenbosch R, Stavropoulos G, Pender J, Jonkers D, et al.
Anal Chim Acta
. 2020 Sep;
1131:146-155.
PMID: 32928475
Current technological developments have allowed for a significant increase and availability of data. Consequently, this has opened enormous opportunities for the machine learning and data science field, translating into the...
3.
Swiderska-Chadaj Z, de Bel T, Blanchet L, Baidoshvili A, Vossen D, van der Laak J, et al.
Sci Rep
. 2020 Sep;
10(1):14398.
PMID: 32873856
Algorithms can improve the objectivity and efficiency of histopathologic slide analysis. In this paper, we investigated the impact of scanning systems (scanners) and cycle-GAN-based normalization on algorithm performance, by comparing...
4.
Identification of Mycobacterium tuberculosis using volatile biomarkers in culture and exhaled breath
Mellors T, Nasir M, Franchina F, Smolinska A, Blanchet L, Flynn J, et al.
J Breath Res
. 2018 Jun;
13(1):016004.
PMID: 29910196
In this pilot study, volatile molecules produced by cultures of Mycobacterium tuberculosis were evaluated to determine whether they could be used to discriminate between uninfected and M. tuberculosis-infected macaques. Thirty...
5.
Smolinska A, Tedjo D, Blanchet L, Bodelier A, Pierik M, Masclee A, et al.
Anal Chim Acta
. 2018 May;
1025:1-11.
PMID: 29801597
Microbiota composition and its metabolic capacity are very important for host health. Evidence suggests that gut microbiome is involved in the metabolites production by host-microbiome interaction. These metabolites can be...
6.
Mellors T, Blanchet L, Flynn J, Tomko J, OMalley M, Scanga C, et al.
J Appl Physiol (1985)
. 2017 Jan;
122(3):695-701.
PMID: 28057819
Breath is hypothesized to contain clinically relevant information, useful for the diagnosis and monitoring of disease, as well as understanding underlying pathogenesis. Nonhuman primates, such as the cynomolgus macaque, serve...
7.
Blanchet L, Smolinska A
Methods Mol Biol
. 2015 Nov;
1362:209-23.
PMID: 26519180
Proteomics and metabolomics provide key insights into status and dynamics of biological systems. These molecular studies reveal the complex mechanisms involved in disease or aging processes. Invaluable information can be...
8.
Manjeri G, Rodenburg R, Blanchet L, Roelofs S, Nijtmans L, Smeitink J, et al.
J Inherit Metab Dis
. 2015 Aug;
39(1):59-65.
PMID: 26310962
We reported before that the minimal alveolar concentration (MAC) of isoflurane is decreased in complex I-deficient mice lacking the NDUFS4 subunit of the respiratory chain (RC) (1.55 and 0.81% at...
9.
Iannetti E, Willems P, Pellegrini M, Beyrath J, Smeitink J, Blanchet L, et al.
Int J Biochem Cell Biol
. 2015 Feb;
63:66-70.
PMID: 25668473
Mitochondria are double membrane organelles involved in various key cellular processes. Governed by dedicated protein machinery, mitochondria move and continuously fuse and divide. These "mitochondrial dynamics" are bi-directionally linked to...
10.
Blanchet L, Smeitink J, van Emst-de Vries S, Vogels C, Pellegrini M, Jonckheere A, et al.
Sci Rep
. 2015 Jan;
5:8035.
PMID: 25620325
In primary fibroblasts from Leigh Syndrome (LS) patients, isolated mitochondrial complex I deficiency is associated with increased reactive oxygen species levels and mitochondrial morpho-functional changes. Empirical evidence suggests these aberrations...