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John N Campbell

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Articles 35
Citations 1398
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Recent Articles
1.
Liu Y, McDaniel J, Chen C, Yang L, Kipcak A, Savier E, et al.
bioRxiv . 2025 Feb; PMID: 39896595
The superior colliculus (SC), a midbrain sensorimotor hub, is anatomically and functionally similar across vertebrates, but how its cell types have evolved is unclear. Using single-nucleus transcriptomics, we compared the...
2.
Godschall E, Gungul T, Sajonia I, Buyukaksakal A, Ogilvie S, Keeler A, et al.
bioRxiv . 2025 Jan; PMID: 39763823
Glucagon-like peptide-1 receptor agonists (GLP1RAs) effectively reduce body weight and improve metabolic outcomes, yet established peptide-based therapies require injections and complex manufacturing. Small-molecule GLP1RAs promise oral bioavailability and scalable manufacturing,...
3.
Webster A, Becker J, Li C, Schwalbe D, Kerspern D, Karolczak E, et al.
Nat Metab . 2024 Dec; 6(12):2354-2373. PMID: 39627618
Liraglutide and other glucagon-like peptide 1 receptor agonists (GLP-1RAs) are effective weight loss drugs, but how they suppress appetite remains unclear. One potential mechanism is by activating neurons that inhibit...
4.
Schwalbe D, Stornetta D, Abraham-Fan R, Souza G, Jalil M, Crook M, et al.
J Neurosci . 2024 Jun; 44(31). PMID: 38918066
The ventrolateral medulla (VLM) is a crucial region in the brain for visceral and somatic control, serving as a significant source of synaptic input to the spinal cord. Experimental studies...
5.
Gupta D, Burstein A, Schwalbe D, Shankar K, Varshney S, Singh O, et al.
J Clin Invest . 2024 May; 134(10). PMID: 38747294
No abstract available.
6.
Strain M, Conley N, Kauffman L, Espinoza L, Fedorchak S, Martinez P, et al.
iScience . 2024 Feb; 27(3):109137. PMID: 38420585
Cardiovagal neurons (CVNs) innervate cardiac ganglia through the vagus nerve to control cardiac function. Although the cardioinhibitory role of CVNs in nucleus ambiguus (CVN) is well established, the nature and...
7.
Jalil M, Coverdell T, Gutierrez V, Crook M, Shi J, Stornetta D, et al.
bioRxiv . 2024 Jan; PMID: 38168262
The nucleus ambiguus (nAmb) provides parasympathetic control of cardiorespiratory functions as well as motor control of the upper airways and striated esophagus. A subset of nAmb neurons innervates the heart...
8.
Gupta D, Burstein A, Schwalbe D, Shankar K, Varshney S, Singh O, et al.
J Clin Invest . 2023 Dec; 133(24). PMID: 38099492
Ghrelin exerts key effects on islet hormone secretion to regulate blood glucose levels. Here, we sought to determine whether ghrelin's effects on islets extend to the alteration of islet size...
9.
Strain M, Conley N, Kauffman L, Espinoza L, Fedorchak S, Martinez P, et al.
bioRxiv . 2023 Nov; PMID: 38014247
Cardiovagal neurons (CVNs) innervate cardiac ganglia through the vagus nerve to control cardiac function. Although the cardioinhibitory role of CVNs in nucleus ambiguus (CVN) is well established, the nature and...
10.
Tang Q, Godschall E, Brennan C, Zhang Q, Abraham-Fan R, Williams S, et al.
Sci Adv . 2023 Aug; 9(34):eadh9570. PMID: 37624889
Salient cues, such as the rising sun or availability of food, entrain biological clocks for behavioral adaptation. The mechanisms underlying entrainment to food availability remain elusive. Using single-nucleus RNA sequencing...