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Linlin M Chen

Explore the profile of Linlin M Chen including associated specialties, affiliations and a list of published articles. Areas
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Articles 4
Citations 1292
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Recent Articles
1.
Marshall J, Doughty B, Subramanian V, Guckelberger P, Wang Q, Chen L, et al.
Proc Natl Acad Sci U S A . 2020 Dec; 117(52):33404-33413. PMID: 33376219
Single-cell quantification of RNAs is important for understanding cellular heterogeneity and gene regulation, yet current approaches suffer from low sensitivity for individual transcripts, limiting their utility for many applications. Here...
2.
Banerjee A, Blanco M, Bruce E, Honson D, Chen L, Chow A, et al.
Cell . 2020 Oct; 183(5):1325-1339.e21. PMID: 33080218
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a recently identified coronavirus that causes the respiratory disease known as coronavirus disease 2019 (COVID-19). Despite the urgent need, we still do...
3.
Rodriques S, Chen L, Liu S, Zhong E, Scherrer J, Boyden E, et al.
Nat Biotechnol . 2020 Oct; 39(3):320-325. PMID: 33077959
Current approaches to single-cell RNA sequencing (RNA-seq) provide only limited information about the dynamics of gene expression. Here we present RNA timestamps, a method for inferring the age of individual...
4.
Rodriques S, Stickels R, Goeva A, Martin C, Murray E, Vanderburg C, et al.
Science . 2019 Mar; 363(6434):1463-1467. PMID: 30923225
Spatial positions of cells in tissues strongly influence function, yet a high-throughput, genome-wide readout of gene expression with cellular resolution is lacking. We developed Slide-seq, a method for transferring RNA...